Protein Alignment Cyp4c3 and Cyp4v3

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 528
• Identity: 249/528 - (47%)
• Similarity: 346/528 - (65%)
• Gaps: 17/528 - (3%)

  Fly     9 LMAESILLSKVGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPA-AMPFLGNAIE 72
            |..:.:||......:| .:..|:.:  ||...||.|    :|..:.:..||..| |.|.:|:|:.
Mouse     8 LSGQKLLLWGAASAVS-LAGATILI--SIFPMLVSY----ARKWQQMRSIPSVARAYPLVGHALY 65

  Fly    73 MNVDHDELFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHP 137
            |..::.|.|.::|...:.: ..:.|.::|.|..|.|.|::.|.||.||.|.|.::||..|.:|.|
Mouse    66 MKPNNAEFFQQLIYYTEEF-RHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQP 129

  Fly   138 WLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVTL 202
            |||.||||||..||.:|||:|||.|||.||::|:||.|||:.:|..||...|..||||.|.|:||
Mouse   130 WLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYITL 194

  Fly   203 CTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYIN 267
            |.|||:||||||:.|.||||::||||:.||.:..::..|....||..|..:.:..|.:.|:..:.
Mouse   195 CALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLK 259

  Fly   268 TLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDAS-KEGTVLSNED 331
            .||.|:|.||.||..|....::.........|      .|.||.||||||:..: :||..||.||
Mouse   260 CLHTFTNNVIAERVKERKAEEDWTGAGRGPIP------SKNKRKAFLDLLLSVTDEEGNRLSQED 318

  Fly   332 IREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLE 396
            ||||||||||||||||:|||:|:|:|||.:||.|.:|.:|||.:|| ....|.|:::|..::||:
Mouse   319 IREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFG-RSHRPVTLEDLKKLKYLD 382

  Fly   397 CCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPE 461
            |.||::||:|||||:.||.:.||..:||..|..||:|||:.|||||:||.||.||:|.|:.|.||
Mouse   383 CVIKETLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPE 447

  Fly   462 NCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDG 526
            |..||||:||:|||||||||||||||::|||.:::.:||::.:|:..:||:|.|.|:|||||.:|
Mouse   448 NSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLILRPNNG 512

  Fly   527 LRVKITPR 534
            :.:|:..|
Mouse   513 IWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	235/473 (50%)
Cyp4v3	NP_598730.1	p450	51..517	CDD:278495	235/473 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844920
Domainoid	1	1.000	460	1.000	Domainoid score	I483
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133054
Inparanoid	1	1.050	471	1.000	Inparanoid score	I1498
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		oto93377
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4308
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.830