DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15547 and nme7

DIOPT Version :9

Sequence 1:	NP_651833.1	Gene:	CG15547 / 43661	FlyBaseID:	FBgn0039809	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_571004.2	Gene:	nme7 / 30086	ZFINID:	ZDB-GENE-000210-35	Length:	374	Species:	Danio rerio

Alignment Length:	269	Identity:	55/269 - (20%)
Similarity:	101/269 - (37%)	Gaps:	59/269 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ENSLFIIKPDYLHKRRPVLLKLLAEGFQIQGNRRIAFSPETAAEFYADYADEKGFMLEVILLSKG 67
            |.:|.:||||.:.|...::..:......:...:....:.:.||:||.::..:..|...|..:|.|
Zfish    90 ERTLAMIKPDAVSKVGDIIQMIYDANLIVTKAKMTKLTWKQAADFYMEHQSKSFFNNLVQFVSSG 154

  Fly    68 VSEAFIVTKENAV----------------QELLNIMICYFGSASDLERNI-HVTKNSYSVAREIN 115
            ...|..:..:.||                :|..:.:...||  :|..:|. |.:.:..|.|||:.
Zfish   155 PVIAMELMGDEAVSTWRKVLGPTDSGVAQKEAAHSLRGQFG--TDGTKNAGHGSDSLASAARELE 217

  Fly   116 FIFPN-----------------YIHEPHQMFDHNNFCNRPMLKPLLEEIYDI----MQNTDCSQE 159
            :.||:                 .|.:||.:   :......:||.::|..::|    |.|.|.:..
Zfish   218 YFFPSTAGHGLSNTAKYSDCTCCIIKPHAI---SEALTGKILKSIIENGFEISALQMFNMDRANA 279

  Fly   160 NWKVRVSDYLVRSNPKMPEISNQCQQRPDVAIQDKSQQTTMTY------APKPSARAAQP----- 213
            ...:.|...:|....||  :...| ..|.:|::..:.....|:      |....||..:|
Zfish   280 EEFLEVYKGVVAEYTKM--VDELC-SGPCMALEIHATDAPRTFREFCGPADPEIARHLRPKTLRA 341

  Fly   214 --GVKKTQS 220
              |..|.|:
Zfish   342 LYGKNKLQN 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15547	NP_651833.1	NDK	3..120	CDD:197791	29/133 (22%)
CG15547	NP_651833.1	NDPk	3..119	CDD:260363	28/132 (21%)
nme7	NP_571004.2	DM10	1..89	CDD:128921
		NDPk7A	90..220	CDD:239878	28/131 (21%)
		NDPk7B	236..369	CDD:239875	25/121 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.860