DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15547 and NME7

DIOPT Version :9

Sequence 1:	NP_651833.1	Gene:	CG15547 / 43661	FlyBaseID:	FBgn0039809	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_037462.1	Gene:	NME7 / 29922	HGNCID:	20461	Length:	376	Species:	Homo sapiens

Alignment Length:	302	Identity:	60/302 - (19%)
Similarity:	106/302 - (35%)	Gaps:	97/302 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ENSLFIIKPDYLHKRRPVLLKLLAEGFQIQGNRRIAFSPETAAEFYADYADEKGFMLEVILLSKG 67
            |.:|.:||||.:.|...::..:...||.|...:.:..|.:.|.:|:.|:.....|...:..::.|
Human    92 EKTLALIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 156

  Fly    68 VSEAFIVTKENAVQELLNIM----------------ICYFGSASDLERN-IHVTKNSYSVAREIN 115
            ...|..:.:::|:.|...::                ...||  :|..|| .|...:..|.|||:.
Human   157 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFG--TDGIRNAAHGPDSFASAAREME 219

  Fly   116 FIFPN-----------------YIHEPH------------------------QMFDHNNFCNRPM 139
            ..||:                 .|.:||                        |||:        |
Human   220 LFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFN--------M 276

  Fly   140 LKPLLEEIYDIMQNTDCSQENWKVRVSDYLVRSNPKMPEISNQCQQRPDVAIQDKSQQTTMTY-- 202
            .:..:||.|::          :|..|::|        .::..:....|.||::.:....|.|:
Human   277 DRVNVEEFYEV----------YKGVVTEY--------HDMVTEMYSGPCVAMEIQQNNATKTFRE 323

  Fly   203 ----APKPSARAAQPGV-----KKTQSSSAPLSTTSPHSSML 235
                |....||..:||.     .||:..:|...|..|...:|
Human   324 FCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLL 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15547	NP_651833.1	NDK	3..120	CDD:197791	30/133 (23%)
CG15547	NP_651833.1	NDPk	3..119	CDD:260363	29/132 (22%)
NME7	NP_037462.1	DM10	3..91	CDD:128921
		NDPk7A	92..222	CDD:239878	29/131 (22%)
		NDPk7B	238..371	CDD:239875	29/154 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770