DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12071 and MGP

DIOPT Version :9

Sequence 1:	NP_651832.3	Gene:	CG12071 / 43660	FlyBaseID:	FBgn0039808	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_171880.1	Gene:	MGP / 839396	AraportID:	AT1G03840	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	84/466 - (18%)
Similarity:	144/466 - (30%)	Gaps:	179/466 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 YICEVCNKAFARRDKLVIHMNKFKHVTPTNIAPLGKRLNNMVKKKEQPDPPPEDNKQSLELQLQQ 277
            ::||:|.|.|.|...|.:|                :|.:|:..|.:|        :.|.|:   :
plant    70 FLCEICGKGFQRDQNLQLH----------------RRGHNLPWKLKQ--------RTSKEV---R 107

  Fly   278 QAVQVAAQNIIVQ----SAQGAPTSIPGIIIPHHQQQLSWTCELCGRMFSSRDEWSIHAK----- 333
            :.|.|..:...|.    .|.|..|.|.......|.:: .|.||.|.:.::.:.:|..|:|
plant   108 KRVYVCPEKSCVHHHPTRALGDLTGIKKHFCRKHGEK-KWKCEKCAKRYAVQSDWKAHSKTCGTR 171

  Fly   334 -----------------SHLEYXQPERLVAESTKPAAAAAGV--IAKTTSSNNSRNYQMDA---- 375
                             :|..: .   .:||.|....||:.:  .|.|..||.:.:|.|..
plant   172 EYRCDCGTIFSRRDSFITHRAFCD---ALAEETARLNAASHLKSFAATAGSNLNYHYLMGTLIPS 233

  Fly   376 -------------------NQNQIQMEAQARKQKIIIQNQMIL------NASHQQQQQPQQHPQQ 415
                               :.:|..:.......:.:::....|      |.:|.||...:.....
plant   234 PSLPQPPSFPFGPPQPQHHHHHQFPITTNNFDHQDVMKPASTLSLWSGGNINHHQQVTIEDRMAP 298

  Fly   416 QQHQQQQQQHVAHGKKAARKHQQHLQQQQQQQQQQQQQQQQQQQQTSAPMYNNN-----SSSNHN 475
            |.|..|:..:...|.  |..|.:.:....                 |...::||     |..|.|
plant   299 QPHSPQEDYNWVFGN--ANNHGELITTSD-----------------SLITHDNNINIVQSKENAN 344

  Fly   476 GNNQSQEVSVP---------------VSHIIAN-------------------SPTA------ATY 500
            |   :..:|||               .|..:||                   |||.      :.|
plant   345 G---ATSLSVPSLFSSVDQITQDANAASVAVANMSATALLQKAAQMGATSSTSPTTTITTDQSAY 406

  Fly   501 MQAQLS-----------------------EHASNMQHGMPIVTYNGNQYCVITRAPDL-DVEAMQ 541
            :|:..|                       |..||..:|:..:....|...|::...:| :....:
plant   407 LQSFASKSNQIVEDGGSDRFFASFGSNSVELMSNNNNGLHEIGNPRNGVTVVSGMGELQNYPWKR 471

  Fly   542 KPLDYGHAAGG 552
            :.:|.|:|.||
plant   472 RRVDIGNAGGG 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12071	NP_651832.3	zf-C2H2	185..207	CDD:278523
		C2H2 Zn finger	187..207	CDD:275368
		zf-H2C2_2	200..224	CDD:290200	5/10 (50%)
		C2H2 Zn finger	215..232	CDD:275368	7/16 (44%)
MGP	NP_171880.1	C2H2 Zn finger	72..92	CDD:275368	9/35 (26%)
		C2H2 Zn finger	113..141	CDD:275368	5/27 (19%)
		C2H2 Zn finger	148..167	CDD:275368	5/18 (28%)
		C2H2 Zn finger	175..191	CDD:275368	0/15 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I2683
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050