Protein Alignment CG12071 and ZNF41

DIOPT Version :10

• Sequence 1: NP_651832.3
• Gene: CG12071 / 43660
• FlyBaseID: FBgn0039808
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001311084.1
• Gene: ZNF41 / 7592
• HGNCID: 13107
• Length: 821
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 61/243 - (25%)
• Similarity: 94/243 - (38%)
• Gaps: 52/243 - (21%)

  Fly   157 SRLKALQQVQQASSGVRKTNPSKSTNKAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKA 221
            ||||..|:             |....:.:||..|||...:|..|::|.|||||||||:|..|.||
Human   606 SRLKIHQK-------------SHIGERHYECKDCGKAFIQKSTLSVHQRIHTGEKPYVCPECGKA 657

  Fly   222 FARRDKLVIHMNKFKHVTPTNIAPLGKRLNNMVKKKEQPDPPPEDNKQSLELQLQQQAVQVAAQN 286
            |.::...:.|........|...:..||    ...||.|             |::.|:.......|
Human   658 FIQKSHFIAHHRIHTGEKPYECSDCGK----CFTKKSQ-------------LRVHQKIHTGEKPN 705

  Fly   287 IIVQSAQGAPTSIPGIIIPH---HQQQLSWTCELCGRMFSSRDEWSIHAKSHLEYXQPE------ 342
            |..:.  |...:....:|.|   |.::..:.|..||:.|:.:...:||.|||......|
Human   706 ICAEC--GKAFTDRSNLITHQKIHTREKPYECGDCGKTFTWKSRLNIHQKSHTGERHYECSKCGK 768

  Fly   343 -----------RLVAESTKPAAAAAGVIAKTTSSNNSRNYQMDANQNQ 379
                       :::....||.|......|.|..||..::.:|.:.:.:
Human   769 AFIQKATLSMHQIIHTGKKPYACTECQKAFTDRSNLIKHQKMHSGEKR 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12071	NP_651832.3	zf-C2H2	185..207	CDD:395048	9/21 (43%)
		C2H2 Zn finger	187..207	CDD:275368	8/19 (42%)
		zf-H2C2_2	200..224	CDD:463886	16/23 (70%)
		C2H2 Zn finger	215..232	CDD:275368	5/16 (31%)
ZNF41	NP_001311084.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		KRAB	69..129	CDD:214630
		C2H2 Zn finger	315..335	CDD:275368
		COG5048	346..768	CDD:227381	53/193 (27%)
		C2H2 Zn finger	371..391	CDD:275368
		C2H2 Zn finger	399..419	CDD:275368
		C2H2 Zn finger	427..447	CDD:275368
		C2H2 Zn finger	455..475	CDD:275368
		C2H2 Zn finger	483..503	CDD:275368
		C2H2 Zn finger	511..531	CDD:275368
		C2H2 Zn finger	539..559	CDD:275368
		C2H2 Zn finger	567..587	CDD:275368
		C2H2 Zn finger	595..615	CDD:275368	5/21 (24%)
		C2H2 Zn finger	623..643	CDD:275368	8/19 (42%)
		C2H2 Zn finger	651..671	CDD:275368	6/19 (32%)
		C2H2 Zn finger	679..699	CDD:275368	7/36 (19%)
		C2H2 Zn finger	707..727	CDD:275368	3/21 (14%)
		C2H2 Zn finger	735..755	CDD:275368	7/19 (37%)
		C2H2 Zn finger	763..783	CDD:275368	0/19 (0%)
		C2H2 Zn finger	791..811	CDD:275368	4/19 (21%)