DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12071 and ZNF35

DIOPT Version :9

Sequence 1:NP_651832.3 Gene:CG12071 / 43660 FlyBaseID:FBgn0039808 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_003411.3 Gene:ZNF35 / 7584 HGNCID:13099 Length:527 Species:Homo sapiens


Alignment Length:367 Identity:78/367 - (21%)
Similarity:128/367 - (34%) Gaps:82/367 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 QQNSPTANNNNNSQNNGNMQQQQQQQQQQQQQQQQQQQQQHYAATIKVPQ------------ISS 90
            |:..|.......:...|||.::|:.:::::..:|......|...:.|..:            ::|
Human   143 QKADPQGPELGEACEKGNMLKRQRIKREKKDFRQVIVNDCHLPESFKEEENQKCKKSGGKYSLNS 207

  Fly    91 SNV--AAAAAGESTFTVPDDGMGFEGGVRVLQSLGTWSAAEQLTYNIPKP--------------N 139
            ..|  .....|:..||....|.||.....::        ..|..:...||              |
Human   208 GAVKNPKTQLGQKPFTCSVCGKGFSQSANLV--------VHQRIHTGEKPFECHECGKAFIQSAN 264

  Fly   140 LIPF------TEPYV---EGGSMHPASRLKALQQVQQA---------------SSGVRKTNPSKS 180
            |:..      .:|||   .|.:...:|.|...|::...               ||.:.:......
Human   265 LVVHQRIHTGQKPYVCSKCGKAFTQSSNLTVHQKIHSLEKTFKCNECEKAFSYSSQLARHQKVHI 329

  Fly   181 TNKAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKAFARRDKLVIHMNKFKHVTPTNIAP 245
            |.|.:||..|||...|...|.:|.||||||||:.|..|.|||.:...|::|........|.....
Human   330 TEKCYECNECGKTFTRSSNLIVHQRIHTGEKPFACNDCGKAFTQSANLIVHQRSHTGEKPYECKE 394

  Fly   246 LGKR--------LNNMVKKKEQPDPPPEDNKQSLELQLQQQAVQVAAQNI------IVQSAQGAP 296
            .||.        ::..:...|:|....|..|     ...|.:..:..|.|      .|.:..|..
Human   395 CGKAFSCFSHLIVHQRIHTAEKPYDCSECGK-----AFSQLSCLIVHQRIHSGDLPYVCNECGKA 454

  Fly   297 TSIPGIIIPH---HQQQLSWTCELCGRMFSSRDEWSIHAKSH 335
            .:....::.|   |..:..:||..||:.|..|...::|.::|
Human   455 FTCSSYLLIHQRIHNGEKPYTCNECGKAFRQRSSLTVHQRTH 496

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12071NP_651832.3 zf-C2H2 185..207 CDD:278523 9/21 (43%)
C2H2 Zn finger 187..207 CDD:275368 8/19 (42%)
zf-H2C2_2 200..224 CDD:290200 15/23 (65%)
C2H2 Zn finger 215..232 CDD:275368 6/16 (38%)
ZNF35NP_003411.3 Globular domain 9..221 12/77 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..38
COG5048 <214..369 CDD:227381 40/162 (25%)
C2H2 Zn finger 224..244 CDD:275368 4/27 (15%)
C2H2 Zn finger 252..272 CDD:275368 2/19 (11%)
C2H2 Zn finger 280..300 CDD:275368 4/19 (21%)
C2H2 Zn finger 308..328 CDD:275368 2/19 (11%)
C2H2 Zn finger 336..356 CDD:275368 8/19 (42%)
C2H2 Zn finger 364..384 CDD:275368 7/19 (37%)
COG5048 372..>449 CDD:227381 13/81 (16%)
C2H2 Zn finger 392..412 CDD:275368 2/19 (11%)
C2H2 Zn finger 420..440 CDD:275368 4/24 (17%)
C2H2 Zn finger 448..468 CDD:275368 2/19 (11%)
zf-H2C2_2 460..485 CDD:316026 7/24 (29%)
zf-C2H2 474..496 CDD:306579 7/21 (33%)
C2H2 Zn finger 476..496 CDD:275368 6/19 (32%)
zf-H2C2_2 488..513 CDD:316026 2/9 (22%)
C2H2 Zn finger 504..524 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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