Protein Alignment CG12071 and ZNF182

DIOPT Version :10

• Sequence 1: NP_651832.3
• Gene: CG12071 / 43660
• FlyBaseID: FBgn0039808
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_008893.1
• Gene: ZNF182 / 7569
• HGNCID: 13001
• Length: 639
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 72/304 - (23%)
• Similarity: 108/304 - (35%)
• Gaps: 95/304 - (31%)

  Fly    64 QQQQQQQQQQQQQQHYAATIKVPQISSSNVAAAAAGE----------STFTV-----PDDGMGFE 113
            |..:|.::|.|..|.....::|.......:...:|.:          ||..|     ||....|
Human   100 QVDEQIERQHQDDQDKCLLMQVGFSDKKTIITKSARDCHEFGNILHLSTNLVASIQRPDKHESF- 163

  Fly   114 GGVRVLQSLGTW--SAAE------------QLTYNIPKPNLIPFTEPYVEGGSMHPASRLKALQQ 164
             |..::.:|..:  |:||            ...|....|.:.|:  .|.|.|.  ...|.|.|..
Human   164 -GNNMVDNLDLFSRSSAENKYDNGCAKLFFHTEYEKTNPGMKPY--GYKECGK--GLRRKKGLSL 223

  Fly   165 VQQASSGVRKTNPSKSTNKAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKAFARRDKLV 229
            .|:..:|          .|.||||.|.|..::|..|.:|.|.||||||:.|..|.|||:::.:|:
Human   224 HQRIKNG----------EKPFECTACRKTFSKKSHLIVHWRTHTGEKPFGCTECGKAFSQKSQLI 278

  Fly   230 IHMNKFKHVTPTNIAPLGKRLNNMVKKKEQPDPPPEDNKQSLELQLQQQAVQVAAQNIIVQSAQG 294
            ||:.     |.|.               |:|...||..|...|
Human   279 IHLR-----THTG---------------ERPFECPECGKAFRE---------------------- 301

  Fly   295 APTSIPGIIIPH---HQQQLSWTCELCGRMFSSRDEWSIHAKSH 335
                 ...:|.|   |..:..:.|..||:.|:.:....:|.|:|
Human   302 -----KSTVIIHYRTHTGEKPYECNECGKAFTQKSNLIVHQKTH 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12071	NP_651832.3	zf-C2H2	185..207	CDD:395048	10/21 (48%)
		C2H2 Zn finger	187..207	CDD:275368	8/19 (42%)
		zf-H2C2_2	200..224	CDD:463886	14/23 (61%)
		C2H2 Zn finger	215..232	CDD:275368	7/16 (44%)
ZNF182	NP_008893.1	KRAB	27..85	CDD:214630
		C2H2 Zn finger	209..228	CDD:275368	6/20 (30%)
		COG5048	232..620	CDD:227381	43/156 (28%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		C2H2 Zn finger	264..284	CDD:275368	8/24 (33%)
		C2H2 Zn finger	292..312	CDD:275368	6/46 (13%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	619..639