DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12071 and ZNF71

DIOPT Version :9

Sequence 1:NP_651832.3 Gene:CG12071 / 43660 FlyBaseID:FBgn0039808 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001357144.1 Gene:ZNF71 / 58491 HGNCID:13141 Length:549 Species:Homo sapiens


Alignment Length:374 Identity:78/374 - (20%)
Similarity:123/374 - (32%) Gaps:113/374 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 QQQQQQQQQQQQQQQQQQQQQHYAATIKV------------PQISSSNVAAAAAGESTFTVPDDG 109
            |::.||.:..|:...:....::|...:.:            |:...|....:..||:|      |
Human    25 QEEWQQLEPAQKDLYRDVMLENYRNLVSLDWETRPEMKELDPKNDISEDKLSVVGEAT------G 83

  Fly   110 MGFEGGVRVLQSLGTW------------SAAEQLTYNIPKPN----------------------L 140
            .....|.|...|.|.|            :.||.....||:.|                      |
Human    84 GPTRNGARGPGSEGVWEPGSWPERPRGDAGAEWEPLGIPQGNKLLGGSVPACHELKAFANQGCVL 148

  Fly   141 IP--FTEPYVEGGSMHPASRLKALQQVQ------------------------QASSGVRKTNPSK 179
            :|  ..:| .|.|:..|..|.|......                        ..||.:.|.....
Human   149 VPPRLDDP-TEKGACPPVRRGKNFSSTSDLSKPPMPCEEKKTYDCSECGKAFSRSSSLIKHQRIH 212

  Fly   180 STNKAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKAFARRDKLVIHMNKFKHVTPTNIA 244
            :..|.|||..|||....:..||||.|:|||||||.|..|.|||::|..|.:|........|....
Human   213 TGEKPFECDTCGKHFIERSSLTIHQRVHTGEKPYACGDCGKAFSQRMNLTVHQRTHTGEKPYVCD 277

  Fly   245 PLGKRL--------NNMVKKKEQPDPPPEDNK---QSLELQLQQ------------QAVQVAAQN 286
            ..||..        :..:...|:|....:..|   |::.|.:.|            :..:..:||
Human   278 VCGKAFRKTSSLTQHERIHTGEKPYACGDCGKAFSQNMHLIVHQRTHTGEKPYVCPECGRAFSQN 342

  Fly   287 IIVQSAQGAPTSIPGIIIPHHQQQLSWTCELCGRMFSSRDEWSIHAKSH 335
            :.:...|..           |..:..:.|:.||:.|:.....::|.::|
Human   343 MHLTEHQRT-----------HTGEKPYACKECGKAFNKSSSLTLHQRNH 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12071NP_651832.3 zf-C2H2 185..207 CDD:278523 11/21 (52%)
C2H2 Zn finger 187..207 CDD:275368 9/19 (47%)
zf-H2C2_2 200..224 CDD:290200 17/23 (74%)
C2H2 Zn finger 215..232 CDD:275368 7/16 (44%)
ZNF71NP_001357144.1 KRAB 13..54 CDD:334504 5/28 (18%)
C2H2 Zn finger 168..184 CDD:275368 1/15 (7%)
COG5048 170..544 CDD:227381 49/222 (22%)
C2H2 Zn finger 192..212 CDD:275368 3/19 (16%)
C2H2 Zn finger 220..240 CDD:275368 9/19 (47%)
C2H2 Zn finger 248..268 CDD:275368 8/19 (42%)
C2H2 Zn finger 276..296 CDD:275368 2/19 (11%)
C2H2 Zn finger 304..324 CDD:275368 4/19 (21%)
C2H2 Zn finger 332..352 CDD:275368 3/30 (10%)
C2H2 Zn finger 360..380 CDD:275368 5/19 (26%)
C2H2 Zn finger 388..408 CDD:275368
C2H2 Zn finger 416..436 CDD:275368
C2H2 Zn finger 444..464 CDD:275368
C2H2 Zn finger 472..492 CDD:275368
C2H2 Zn finger 500..520 CDD:275368
C2H2 Zn finger 528..548 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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