DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12071 and CG11247

DIOPT Version :9

Sequence 1:	NP_651832.3	Gene:	CG12071 / 43660	FlyBaseID:	FBgn0039808	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	55/271 - (20%)
Similarity:	106/271 - (39%)	Gaps:	36/271 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 KAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKAFARRDKLVIHM-----NKFKHVTPTN 242
            |.|.|:.|.|..|.|::|.:|||:|:|||||.|::|:|.|||..:|..||     ...:....|.
  Fly   148 KQFVCSQCPKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSHHKTSIQQFNCTK 212

  Fly   243 IAPLGKRLNNMVKKKEQPDPPPED----------NKQSLELQLQQQAVQVAAQNIIVQSAQGAPT 297
            .:.......|:....|:.:...|.          |:.:|...:.|:..::......:......|.
  Fly   213 CSASFSTNANLRVHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHKMIEPD 277

  Fly   298 SIPGIIIPHHQQQLSWTCELCGRMFSSRDEWSIHAKSHLEYXQPERLVAESTKPAAAAAGVIAKT 362
            ......:..|....:..||:|...|:.:.::::|.:.|             |........:..:|
  Fly   278 EDLATHMQRHTAVKTHVCEVCNTYFTQKSQYNVHMRMH-------------TGERPYQCRICHQT 329

  Fly   363 TSSNNSRNYQMDANQNQIQMEAQARKQKIIIQNQMILNASHQQQQQPQQHPQQQQ--H-----QQ 420
            .:.::.....:..:..:.....|..:.::.. :|:....:|.::...||.|...:  |     :.
  Fly   330 FAHSSVLKLHIRKHTGEKPFRCQLCEDEVAF-SQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKV 393

  Fly   421 QQQQHVAHGKK 431
            :.|.||.|..|
  Fly   394 ELQSHVEHCAK 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12071	NP_651832.3	zf-C2H2	185..207	CDD:278523	10/21 (48%)
		C2H2 Zn finger	187..207	CDD:275368	9/19 (47%)
		zf-H2C2_2	200..224	CDD:290200	14/23 (61%)
		C2H2 Zn finger	215..232	CDD:275368	7/16 (44%)
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	30/98 (31%)
		C2H2 Zn finger	95..115	CDD:275368
		zf-H2C2_2	107..132	CDD:290200
		C2H2 Zn finger	123..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368	9/19 (47%)
		zf-H2C2_2	165..189	CDD:290200	14/23 (61%)
		C2H2 Zn finger	180..200	CDD:275368	9/19 (47%)
		COG5048	<192..369	CDD:227381	22/190 (12%)
		C2H2 Zn finger	210..230	CDD:275370	3/19 (16%)
		C2H2 Zn finger	238..260	CDD:275371	3/21 (14%)
		C2H2 Zn finger	267..287	CDD:275368	1/19 (5%)
		C2H2 Zn finger	295..315	CDD:275368	5/19 (26%)
		zf-H2C2_2	309..332	CDD:290200	4/35 (11%)
		C2H2 Zn finger	323..343	CDD:275368	1/19 (5%)
		C2H2 Zn finger	351..374	CDD:275368	3/23 (13%)
		C2H2 Zn finger	382..399	CDD:275368	2/16 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100