DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12071 and CG1602

DIOPT Version :9

Sequence 1:	NP_651832.3	Gene:	CG12071 / 43660	FlyBaseID:	FBgn0039808	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	73/352 - (20%)
Similarity:	113/352 - (32%)	Gaps:	132/352 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 NSPTANNNNNSQNNGNMQQQQQQQQQQQQQQQQQQQQQHYAATIKVPQISSSNVAAAAAGESTFT 104
            |.|...::|:.:.: ||..::|..:..             ||.|.||.:..::
  Fly   279 NFPQLYDSNHKEFS-NMSSRKQAYESM-------------AAEISVPNVDINS------------ 317

  Fly   105 VPDDGMGFEGGVRVLQSLGTW------------SAAEQLTYNIPKPNLIPFTEPYVEGGSMHPAS 157
              ||..      |.:|:|..|            |.||:.               |:|.....||.
  Fly   318 --DDIF------RAIQNLRQWYYKNTKHAIYAGSTAEKF---------------YLEVCRFMPAK 359

  Fly   158 RLKA------LQQVQQA----SSGVRKTN-----PSKST---------------------NKAFE 186
            ..|.      ..|:..:    .|.:.|.:     |.|.|                     .|..:
  Fly   360 MYKQRLVCEFCHQITSSDHVLQSHIFKAHNIGELPFKCTLCDRSFVGRCELANHIQRVHIGKTHK 424

  Fly   187 CTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKAFARRDKLVIH-------MNKFKHVTPTNIA 244
            ||.|.:..|....|.:|:|.|||.|||:||.|.|||..|.::.:|       :..||    ..:.
  Fly   425 CTHCERSFAVMSDLQLHIRTHTGHKPYVCEHCGKAFRLRSQMTLHVTAIHTKIRAFK----CTMC 485

  Fly   245 PLGKRLNNMVKKKEQPDPPPEDNKQSLELQLQQQAVQVAAQNIIVQSAQGAPTSIPGIIIPH--- 306
            |     .:.|||.:..|      .....|.::.:...|..:......|          :|.|
  Fly   486 P-----KDFVKKVDLSD------HIKGHLNIRDKICSVCGKGFTSCHA----------LIRHRQI 529

  Fly   307 HQQQLSWTCELCGRMFSSRDEWSIHAK 333
            |.:...:.|:||...||.....:.|.|
  Fly   530 HSEVKKFVCKLCDSRFSQFVGLNTHMK 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12071	NP_651832.3	zf-C2H2	185..207	CDD:278523	7/21 (33%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		zf-H2C2_2	200..224	CDD:290200	15/23 (65%)
		C2H2 Zn finger	215..232	CDD:275368	8/23 (35%)
CG1602	NP_610291.2	GT1	157..244	CDD:304916
		MADF_DNA_bdg	273..356	CDD:287510	22/125 (18%)
		C2H2 Zn finger	367..388	CDD:275368	3/20 (15%)
		C2H2 Zn finger	397..418	CDD:275368	1/20 (5%)
		COG5048	<423..554	CDD:227381	39/155 (25%)
		C2H2 Zn finger	425..445	CDD:275368	7/19 (37%)
		zf-H2C2_2	437..460	CDD:290200	13/22 (59%)
		C2H2 Zn finger	453..470	CDD:275368	7/16 (44%)
		C2H2 Zn finger	482..502	CDD:275368	5/30 (17%)
		C2H2 Zn finger	510..530	CDD:275368	4/29 (14%)
		C2H2 Zn finger	538..559	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100