DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12071 and LOC108183935

DIOPT Version :9

Sequence 1:	NP_651832.3	Gene:	CG12071 / 43660	FlyBaseID:	FBgn0039808	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_017211249.1	Gene:	LOC108183935 / 108183935	-ID:	-	Length:	358	Species:	Danio rerio

Alignment Length:	398	Identity:	82/398 - (20%)
Similarity:	137/398 - (34%)	Gaps:	97/398 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ESTFTVPDDGMGFEGGVRVL-QSLGTWSAAEQLTYNI---PKPNLIPFTEPYVEGGSMHPASRL- 159
            |.||||..:.:..:..:.:| :.....:..|::..::   .||.|...|..........|:...
Zfish    14 EETFTVKQEDLQEQTDLMLLKEKTHQQNEMEEIQQDMTTDEKPTLTKKTLSRGRHRKSKPSCNFS 78

  Fly   160 -----KALQQVQQASSGVRKTNPSKSTNKAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCN 219
                 |:..|..:....:|    ..:..||:.|..|||.......||:||||||||:||.|:.|.
Zfish    79 CKQCGKSFSQKPKLDVHIR----DHTREKAYTCKQCGKSFYNTRNLTVHMRIHTGERPYTCQQCG 139

  Fly   220 KAFARRDKLVIHMNKFKHVTPTNIAPLGK--------RLNNMVKKKEQPDPPPEDNK---QSLEL 273
            |:|.:...|.:||.......|......||        .::..:...|:|...|:..|   |:..|
Zfish   140 KSFHKTGNLTVHMRIHTGERPYTCQQCGKSFQTTGNLTVHMRIHTGEKPYSCPQCGKSYNQNSNL 204

  Fly   274 QLQQQAVQVAAQNIIVQSAQGAPTSIPGIIIPHHQQQLSWTCELCGRMFSSRDEWSIHAKSHL-- 336
            ::..:.                           |....::.|..||:.|:.:....:|.:.|.
Zfish   205 EVHMRT---------------------------HNGGRTFVCTQCGKSFAQKQNLDLHMRIHTGE 242

  Fly   337 -EYXQPE--------------RLVAESTKP-AAAAAGVIAKTTSSNNSRNYQMDANQNQI----Q 381
             .|...|              .:|....|| |.|..|  ...|...|.||: |:.:...|    .
Zfish   243 KPYTCTECGKSFPYKSTLKHHMIVHTGEKPFACAQCG--KSFTCKANLRNH-MNGHTGTIVFTCD 304

  Fly   382 MEAQARKQKIIIQNQMILNASHQQQQQPQQHPQQQQHQQQQQQHVAHGKKAARKHQQHLQQQQQQ 446
            :..::...|..|:|.|                  :.|..::...:..||  ..||::.|....:.
Zfish   305 LCGKSLTHKYSIKNHM------------------KTHSGERFICIECGK--GFKHKRSLSNHMEL 349

  Fly   447 QQQQQQQQ 454
            ...:|..|
Zfish   350 HNGEQSPQ 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12071	NP_651832.3	zf-C2H2	185..207	CDD:278523	9/21 (43%)
		C2H2 Zn finger	187..207	CDD:275368	9/19 (47%)
		zf-H2C2_2	200..224	CDD:290200	16/23 (70%)
		C2H2 Zn finger	215..232	CDD:275368	5/16 (31%)
LOC108183935	XP_017211249.1	C2H2 Zn finger	79..99	CDD:275368	3/23 (13%)
		C2H2 Zn finger	107..127	CDD:275368	9/19 (47%)
		zf-H2C2_2	119..144	CDD:316026	16/24 (67%)
		C2H2 Zn finger	135..155	CDD:275368	7/19 (37%)
		zf-H2C2_2	147..170	CDD:316026	6/22 (27%)
		C2H2 Zn finger	163..183	CDD:275368	2/19 (11%)
		COG5048	<187..346	CDD:227381	36/208 (17%)
		C2H2 Zn finger	191..211	CDD:275368	4/46 (9%)
		C2H2 Zn finger	219..239	CDD:275368	5/19 (26%)
		C2H2 Zn finger	247..267	CDD:275368	1/19 (5%)
		C2H2 Zn finger	275..295	CDD:275368	7/22 (32%)
		C2H2 Zn finger	303..323	CDD:275368	4/37 (11%)
		C2H2 Zn finger	330..350	CDD:275368	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910