Protein Alignment tll and NR1I3

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_005245750.1
• Gene: NR1I3 / 9970
• HGNCID: 7969
• Length: 429
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 87/382 - (22%)
• Similarity: 131/382 - (34%)
• Gaps: 105/382 - (27%)

  Fly    63 RRSRQYVCKS-----QKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMA 122
            :|||:.|.||     ...|.|.|.||.|..|.||||:||.:.||.||.:.....   ..|||
Human   105 KRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEA---LALRR--- 163

  Fly   123 MYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAA-------FQPPPS 180
                |........|.|.::......|            :....|.|..||..       |:||..
Human   164 ----AKQAQRRAQQTPVQLSKEQEEL------------IRTLLGAHTRHMGTMFEQFVQFRPPAH 212

  Fly   181 AAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVN 245
            ..         :.|.|:         ||           |.|..||:.  |..:.....:.:.:.
Human   213 LF---------IHHQPL---------PT-----------LAPVLPLVT--HFADINTFMVLQVIK 246

  Fly   246 WIKSVRAFTELPMPDQLLLLEESWKEF--FILAMAQYLMPMNFAQLLFVYESENANREIMGMVTR 308
            :.|.:..|..||:.||:.||:.:..|.  .:|.....|...||......|..|:..|     |:.
Human   247 FTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR-----VSP 306

  Fly   309 EVHAFQEVLNQLCH-------LNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNS 366
            .|....|.|..|.|       |.:...||..|.|::||..:|             .||
Human   307 TVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP-------------YLT------- 351

  Fly   367 SASAESRGLLESGKVAAMHNDARSALHNYI--QRTHPSQPMRFQTLLGVVQLMHKVS 421
                :..|:.:..::..:..:....|.:||  |:..|.....:..|||::..:..::
Human   352 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	23/58 (40%)
		NR_LBD	215..436	CDD:416257	46/218 (21%)
NR1I3	XP_005245750.1	NR_DBD_like	<108..154	CDD:295381	21/45 (47%)
		NR_LBD_PXR_like	178..427	CDD:132732	58/299 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910