Protein Alignment tll and Nr5a1

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001178028.1
• Gene: Nr5a1 / 83826
• RGDID: 68350
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 482
• Identity: 126/482 - (26%)
• Similarity: 186/482 - (38%)
• Gaps: 128/482 - (26%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFE 98
            |.||.|..||.|||:..|:.|.|||||:::.::.|.|...:.  |.:|||.|.:|..||.:||..
  Rat    13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQS--CKIDKTQRKRCPFCRFQKCLT 75

  Fly    99 VGMNKDAVQHE--RGPRNSTLRRHMAMYK-DAMMGAGEMPQIPAE-ILMNTAALTGFPGVPMPMP 159
            |||..:||:.:  ||.||    :...||| |..:...:..||.|. ..:.|....|.|..|.|.|
  Rat    76 VGMRLEAVRADRMRGGRN----KFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPPP 136

  Fly   160 G--LPQRAGHHPAHMAAFQPPPS------AAAVLDLSVPRVPHHPVHQGHHGFFSPT-------A 209
            .  ||... |.|...|....|||      .|..|.::||. ||.|:    .|:..|.       :
  Rat   137 DYMLPPSL-HAPEPKALVSGPPSGPLGDFGAPSLPMAVPG-PHGPL----AGYLYPAFSNRTIKS 195

  Fly   210 AYMNALATRALPPTPPLMAAEH-------------------------------IKETA------- 236
            .|....|:....|.||....|.                               ::|.|
  Rat   196 EYPEPYASPPQQPGPPYSYPEPFSGGPNVPELILQLLQLEPEEDQVRARIVGCLQEPAKSRPDQP 260

  Fly   237 ---------AEHLFKN-VNWIKSVRAFTELPMPDQLLLLEESWKEFFIL----AMAQY------- 280
                     |:..|.: |:|.:....|.||.:.||:.||:..|.|..:|    ...||
  Rat   261 APFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGKEDSIL 325

  Fly   281 LMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPS 345
            |:.....:|..|  :..|...:..:|.|.    ||::.||..|.:|..|:.||:.:.||
  Rat   326 LVTGQEVELSTV--AVQAGSLLHSLVLRA----QELVLQLHALQLDRQEFVCLKFLILF------ 378

  Fly   346 ASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRF-QT 409
            :...:.|.|.|:                       |......|.:||.:|....:|....:| |.
  Rat   379 SLDVKFLNNHSL-----------------------VKDAQEKANAALLDYTLCHYPHCGDKFQQL 420

  Fly   410 LLGVVQLMHKVSSFTIEELFFRKTIGD 436
            ||.:|::  :..|...:|..:.|.:|:
  Rat   421 LLCLVEV--RALSMQAKEYLYHKHLGN 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	37/84 (44%)
		NR_LBD	215..436	CDD:416257	57/280 (20%)
Nr5a1	NP_001178028.1	NR_DBD_Lrh-1_like	13..105	CDD:143541	41/97 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..149		10/32 (31%)
		NR_LBD_SF-1	224..460	CDD:132755	53/259 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910