Protein Alignment tll and nr1d4b

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001272462.1
• Gene: nr1d4b / 571948
• ZFINID: ZDB-GENE-080403-6
• Length: 576
• Species: Danio rerio
• Alignment Length: 482
• Identity: 111/482 - (23%)
• Similarity: 177/482 - (36%)
• Gaps: 154/482 - (31%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQY-VCKSQKQGLCVVDKTHRNQCRACRLRKCF 97
            ||||.|.:||.|||::||:||.|||:|||:::..| :|...:.  |::.:.:||:|:.||.:||.
Zfish   119 CKVCGDIASGFHYGVHACEGCKGFFRRSIQQNIHYKMCVKNEN--CLIMRMNRNRCQHCRFKKCL 181

  Fly    98 EVGMNKDAVQHERGPRNSTLR--RHMAMY-----KDAMMGAG-----EMPQIPAE---------- 140
            .|||::|||:..|.|:....|  ..|..|     :.|.|..|     |.|..|.:
Zfish   182 SVGMSRDAVRFGRIPKREKQRLLDEMQSYMNSLNESASMDIGCTTPTETPSSPEDGQSEESIGVI 246

  Fly   141 ------ILMNTAALTGFPGVPMPMP------GLPQRAGHHPAHMAAF---QPPPSAAA------- 183
                  |.:|...|.    |.:...      ..|....|||...:.:   .|.|:.:|
Zfish   247 SQAYRNIFVNGEKLQ----VKVDQENNVNNNNNPSSFRHHPMQESGYVQSHPQPNISAQEHSVHS 307

  Fly   184 -VLDLSVPRVP-----HHPVHQ----GHHGF---------FSPTAAY---MNALATRA------L 220
             ...|:..|.|     :.|..|    ||:.|         .:||.:|   .|:.:|:.      |
Zfish   308 TTSCLAQSRCPVANQNNKPTSQVLDNGHYNFPQSSSPSQGTTPTQSYPTKHNSYSTQTQSCPWRL 372

  Fly   221 PP----------TPPLMAAEHIKETAAEH--------LFKNVNWIKSVRAFTELPMPDQLLLLEE 267
            .|          ..|:.:|.|..:...|.        :.:.|.:.||:..|..|...||::||:.
Zfish   373 SPGAKVLACPLNACPVSSASHSSQQVWESFSQCFTPAVKEVVEFAKSIPGFQALSQHDQVMLLKA 437

  Fly   268 --------------SWKEFFILAMAQYLMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLN 318
                          :.||..:..:.....|:::.::|.           ||.:...:..|.|.|.
Zfish   438 GTFQVLMVRFCSLFNAKERTVTFLNGQTYPLSYLRVLG-----------MGNLLDAMFEFSEKLG 491

  Fly   319 QLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAA 383
            .   :.:::.|.....|:.|                             .||:..|:.:.|.|..
Zfish   492 S---MGLEADEMALFMAVVL-----------------------------VSADRSGISDMGAVEQ 524

  Fly   384 MHNDARSALHNYIQRTHPSQPMRFQTL 410
            :..|...||...|.|..|.....|..|
Zfish   525 LQEDLIGALRALITRRKPEDSSLFPKL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	38/83 (46%)
		NR_LBD	215..436	CDD:416257	41/234 (18%)
nr1d4b	NP_001272462.1	NR_DBD_REV_ERB	115..202	CDD:143540	38/84 (45%)
		NR_LBD	386..574	CDD:299703	38/209 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910