Protein Alignment tll and nr1h3

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001017545.2
• Gene: nr1h3 / 548341
• ZFINID: ZDB-GENE-050410-7
• Length: 441
• Species: Danio rerio
• Alignment Length: 459
• Identity: 106/459 - (23%)
• Similarity: 175/459 - (38%)
• Gaps: 111/459 - (24%)

  Fly     5 EGSPDMMDQKYNSVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYV 69
            ||.|         |:.....:.::|.:..|.||.|.:||.||.:.:|:||.|||:||:.:..||.
Zfish    74 EGQP---------VKRKKGPAPKMLGNEVCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAQYS 129

  Fly    70 CKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEM 134
            ||:  .|.|.:|...|.:|:.||||||.|.||.:..|..|...|...:::.
Zfish   130 CKN--SGRCEMDMYMRRKCQQCRLRKCREAGMLEQCVLSEEQIRLKKMKKQ-------------- 178

  Fly   135 PQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHP---AHMAAFQPPPSAAAVLDLSVPRVPHHP 196
                    ....|.|.....|.|.|.:|..|....   ..:.|.|...:..:.:|.  |:|...|
Zfish   179 --------EEETARTSTVATPSPAPEMPPLAPEQQEMIEKLVAMQKQCNKRSFIDR--PKVTPWP 233

  Fly   197 ---------VHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRA 252
                     |.|.....|:..|                :|:.:.|           |::.|.:..
Zfish   234 QSQDPQNREVRQQRFAHFTELA----------------IMSVQEI-----------VDFAKQLPG 271

  Fly   253 FTELPMPDQLLLLEESWKEFFILAMAQYLMP----MNFAQLLFVYESENANREIMGMVTREVHAF 313
            |.||...||:.||:.|..|..:|..::...|    :.|.: .|.|..|:..:  .|:....::..
Zfish   272 FLELTREDQIALLKTSTIEIMLLETSRRYNPAIDSITFLK-DFTYNKEDFAK--AGLQLEFINPI 333

  Fly   314 QEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLES 378
            .|....:..|::|..||..|.||::|....|:....|
Zfish   334 FEFSKGMNDLHLDEAEYALLIAINIFSADRPNVQDHE---------------------------- 370

  Fly   379 GKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLI 443
             .|..:......|||:||:...|:..:.|..:|..:..:..:||...|::|..: :.|..:..|:
Zfish   371 -LVERLQQPYVDALHSYIRIKRPNDHLMFPRMLMKLVSLRTLSSVHSEQVFALR-LQDKKLPPLL 433

  Fly   444 SDMY 447
            |:::
Zfish   434 SEIW 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	38/91 (42%)
		NR_LBD	215..436	CDD:416257	44/224 (20%)
nr1h3	NP_001017545.2	NR_DBD_LXR	74..174	CDD:143534	42/110 (38%)
		NR_LBD_LXR	204..439	CDD:132752	57/296 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910