Protein Alignment tll and PPARD

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001165289.1
• Gene: PPARD / 5467
• HGNCID: 9235
• Length: 441
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 109/485 - (22%)
• Similarity: 194/485 - (40%)
• Gaps: 130/485 - (26%)

  Fly     1 MQSSEGSPDMMDQKYNSVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRS 65
            :..|...|.::||    :::....:|....::.|:||.|.:||.|||::||:||.|||:|:||..
Human    45 LSRSSSPPSLLDQ----LQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMK 105

  Fly    66 RQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMG 130
            .:|. |.::.  |.:.|.:||:|:.||.:||..:||:.:|::..|.|...  :|.:.....|..|
Human   106 LEYE-KCERS--CKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAE--KRKLVAGLTANEG 165

  Fly   131 AGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGH-HPAHMAAF-QPPPSAAAVL----DLSV 189
            :...||:        |.|..|             :.| :.|::..| .....|.::|    ..:.
Human   166 SQYNPQV--------ADLKAF-------------SKHIYNAYLKNFNMTKKKARSILTGKASHTA 209

  Fly   190 PRVPH--HPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHI----KETAAEHLFKNVNWIK 248
            |.|.|  ..:.|...|.       :.......|||...:  :.|:    :.|..|.:.:...:.|
Human   210 PFVIHDIETLWQAEKGL-------VWKQLVNGLPPYKEI--SVHVFYRCQCTTVETVRELTEFAK 265

  Fly   249 SVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLLFVYESEN---ANREIMGMVTREV 310
            |:.:|:.|.:.||:.||:....|..            ||.|..:...:.   ||..  |.||||.
Human   266 SIPSFSSLFLNDQVTLLKYGVHEAI------------FAMLASIVNKDGLLVANGS--GFVTREF 316

  Fly   311 -----HAFQEVLN-------QLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGS 363
                 ..|.:::.       :...|.:|.::      ::||             ..:.||.|
Human   317 LRSLRKPFSDIIEPKFEFAVKFNALELDDSD------LALF-------------IAAIILCG--- 359

  Fly   364 PNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVV-----------QLM 417
                   :..||:...:|.|:.:....||..::|..||.....|..||..:           |:|
Human   360 -------DRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMM 417

  Fly   418 HKVSSFTIEELFFRKTIGDITIVRLISDMY 447
            .::          :||..:.::..|:.::|
Human   418 QRI----------KKTETETSLHPLLQEIY 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	36/91 (40%)
		NR_LBD	215..436	CDD:416257	49/250 (20%)
PPARD	NP_001165289.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		2/8 (25%)
		NR_DBD_Ppar	73..156	CDD:143523	36/87 (41%)
		NR_LBD_PPAR	173..440	CDD:132730	64/340 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910