Protein Alignment tll and nr6a1

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_012823721.1
• Gene: nr6a1 / 493367
• XenbaseID: XB-GENE-487592
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 109/489 - (22%)
• Similarity: 191/489 - (39%)
• Gaps: 130/489 - (26%)

  Fly     9 DMMDQKYNSVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQ 73
            :|.|...:..:::.....|:.... |.:|.|.::|.||||.:|:||.|||||||...|.|.|...
 Frog    30 NMSDLSSDGFKMNSLVDDRVDQRA-CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRD 93

  Fly    74 KQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHE--RGPRNST----------LRRHM----- 121
            |.  ||:.:..||:|:.|||.||.::|||:.|::.:  .|.||.:          :.|.|
 Frog    94 KN--CVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISDEEIERIMSGQEF 156

  Fly   122 -------------AMYKDAMMGAGEMPQIPAEILMNTAA----LTGFP-------GVPMPMPGLP 162
                         :.:.....|..|..| |:.:...:::    |.||.       |.|.||
 Frog   157 EEEANTSWSNNGDSDHSSPGNGVSESNQ-PSPVSTPSSSRSMELNGFGSLRDQYLGTPGPM---- 216

  Fly   163 QRAGHHP--AHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPP 225
                |:.  .|:.::...|:.......|:....|..::|      ..||..:..|:|       |
 Frog   217 ----HYQYLPHLFSYSAHPTLIPTQSRSLDPQSHTLINQ------LLTAEDIEPLST-------P 264

  Fly   226 LMAAEHIKET-----------AAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQ 279
            ::..:..|.|           |.|.||:.:.|:|.:..|.:|.:.|...||..:|:|..:|:...
 Frog   265 MLIEDGYKVTQSELFALLCRLADELLFRQITWVKKLPFFCDLSIKDYTCLLSTTWQELILLSSLT 329

  Fly   280 YLMPMNFAQLLFVYESENANREIMGMVTREVHAF----QEVLNQLCH-------LNIDSTEYECL 333
            ......|..|..|....:.:.:       |:|.|    .||:.:|.:       |.:.:.||.|:
 Frog   330 TYSKQIFGDLADVTSKYSPSED-------ELHRFSEDGMEVMERLIYLFRKFSQLKVSNEEYVCM 387

  Fly   334 RAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQR 398
            :||:...:                             :.:|:....:|..::........::.:.
 Frog   388 KAINFLNQ-----------------------------DIQGISSVSQVEQLNKRYWYVCQDFTEY 423

  Fly   399 THPSQPMRFQTLL----GVVQLMHKVSSFTIEEL 428
            .:|.||.||..|:    .|..:..|:.:..:|:|
 Frog   424 RYPHQPNRFPDLMMCLPEVRYIAGKLVNVPLEQL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	40/103 (39%)
		NR_LBD	215..436	CDD:416257	46/240 (19%)
nr6a1	XP_012823721.1	NR_DBD_GCNF_like	46..135	CDD:143543	39/91 (43%)
		NR_LBD_DHR4_like	251..463	CDD:132751	49/256 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910