DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and ubxn6

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001005818.1	Gene:	ubxn6 / 448295	XenbaseID:	XB-GENE-971811	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	61/313 - (19%)
Similarity:	105/313 - (33%)	Gaps:	83/313 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 GHHPAHMAAFQPPPSAAAVLDLSV-PRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAA 229
            |..|.|..:.....:.|.|....| ||.|             ||.....|.|:.|:.....|...
Frog    16 GAGPGHKLSEDTRENVAKVTKEQVKPRKP-------------PTGEAQIAAASAAMARMESLQGR 67

  Fly   230 EHI---------KETAAEHLFKNV-------NWIKSVRAFTEL---PMPDQLLLLEESWKEFFIL 275
            ..:         ||...:....||       ...||....|.|   |:.|:||..||  :|..|.
Frog    68 TKVQSKDTTTGRKEMIEQKEESNVGPKDIGTTRKKSSSVCTVLFRCPLTDELLRKEE--REGHIR 130

  Fly   276 AMAQYLMPMN--FAQLLFVYESENANREIMGMVTREVHAFQEVL------NQLCHLNIDSTEYE- 331
            .:.|.|...:  .|.:|.:: :.|.:||.:.:.|..:..:...:      .:.|.:.:.:..::
Frog   131 NVLQRLSTTDPTSAAILKIH-TYNKDREKVKLGTETIAKYMNNIISHPEEEKYCRIKLSNKVFQE 194

  Fly   332 ---CL-------RAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHN 386
               ||       .|:...:|:.|.    :||.....:.|..                    |:.|
Frog   195 KISCLEGSHEFFEAVGFEKKTMPG----QDLQEEFFVLGGD--------------------ALKN 235

  Fly   387 DARSALHNYIQRTHPSQPMR--FQTLLGVVQLMHKVSSFTIEELFFRKTIGDI 437
              ..|||.:......::|:|  .:..|.:.....:.:.|.:.:.||..|..:|
Frog   236 --LDALHGHCDALLSAEPLRLSLERQLRIFMPSIEAAHFDLPDDFFNLTAEEI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	48/260 (18%)
ubxn6	NP_001005818.1	PUB_UBXD1	146..249	CDD:198418	19/129 (15%)
ubxn6	NP_001005818.1	TGS	318..395	CDD:330245
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910