DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tll and eg

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_524206.1	Gene:	eg / 40428	FlyBaseID:	FBgn0000560	Length:	373	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	50/185 - (27%)
Similarity:	81/185 - (43%)	Gaps:	28/185 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYV-CKSQKQGLCVVDKTHRNQCRACRLRKCF 97
            ||||.:.::|.|:|.:.|:||..||.|:........ ||  ..|.||::|.:|..|:|||||||.
  Fly     5 CKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCK--HNGDCVINKKNRTACKACRLRKCL 67

  Fly    98 EVGMNKDAVQHERGPRNSTLRRHMAMYKD---------AMMGAGEMPQIPAEILMNTAALTGFPG 153
            .|||:|...::  |.|::..:.|..:.:.         :.:|:|....:.:..|...|.|
  Fly    68 LVGMSKSGSRY--GRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARL----- 125

  Fly   154 VPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPT 208
                     |:|.:........:..|...:....:.||:....|..|..|..||:
  Fly   126 ---------QQASNQARQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPS 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	34/83 (41%)
tll	NP_524596.1	NR_LBD	215..436	CDD:416257
eg	NP_524206.1	NR_DBD_like	3..87	CDD:295381	34/85 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910