DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and ZK418.11

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001022997.1	Gene:	ZK418.11 / 3565390	WormBaseID:	WBGene00044354	Length:	301	Species:	Caenorhabditis elegans

Alignment Length:	220	Identity:	40/220 - (18%)
Similarity:	81/220 - (36%)	Gaps:	79/220 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 LFKNVNWIKSVRAFTELPMPDQL------------LLLEESWKEFFILAMA--QYLMPMNFAQLL 290
            :|.:.:|: ::.|||.|....::            |:|:.|:....|:.||  .|.....|  ::
Worm   106 VFTSHDWV-AIEAFTTLEFMKRIHFVKMLNADEANLILKHSFFTLSIVFMAGRSYFDKKEF--MV 167

  Fly   291 F-----VYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTE 350
            |     |:..|.:::..:.::.| :..  .::::...|.|.:.|: .|..|:.|.:.
Worm   168 FPGKVDVFPEEISDQYPLDLLNR-IRC--RLISKFIELRITTEEF-LLMVITYFCQI-------- 220

  Fly   351 DLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQ------------RTHPSQ 403
                ||:|.||                         .|:..:..|:.            |.....
Worm   221 ----SSMLVGS-------------------------SAKRIIEEYLSIYLSTLGINCNFRFQKHG 256

  Fly   404 PMRFQTLLGVVQLMHKVSSFTIEEL 428
            .:|:..::.:.||:.|    |||:|
Worm   257 RIRYLNIIFLSQLIEK----TIEDL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	40/220 (18%)
ZK418.11	NP_001022997.1	HOLI	118..273	CDD:214658	33/201 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158220
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840