DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and ZK418.10

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001022996.1	Gene:	ZK418.10 / 3565356	WormBaseID:	WBGene00044353	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	42/233 - (18%)
Similarity:	79/233 - (33%)	Gaps:	74/233 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 KETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLLFVYESEN 297
            |.:....:...:|:||.         |..|:...|.|.....|:...::...:|......|..::
Worm    77 KSSVDNAVISTINFIKK---------PPYLVFSMEEWTSINQLSTIDFIKKFDFVNQFSCYSDKS 132

  Fly   298 ------------------------------ANREIMGMVTREV---HAFQEVLNQLCH--LNIDS 327
                                          .|.:|....:.::   |...::.:||..  :.:|.
Worm   133 KFIHGVRFKSAIFSTSMRVFNEKKSYMHFPGNVDIFPEHSSQLFNPHFLNKIRSQLIGKLIELDI 197

  Fly   328 TEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSAL 392
            |:.|.|...:||                  |..:..|:  .|.|.:.||.  |....::   :||
Worm   198 TKNESLLLSALF------------------LCSAVHPD--ISTEGKNLLY--KYQQYYS---AAL 237

  Fly   393 HNYIQRTH-PSQPMRFQTLLGVVQLM----HKVSSFTI 425
            .|:...|: .:.|.|:..||.:.|::    .||::|.|
Worm   238 INHCCLTNQQNAPSRYSELLSLYQIIEETHQKVNNFAI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	42/233 (18%)
ZK418.10	NP_001022996.1	HOLI	105..266	CDD:214658	30/185 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910