Protein Alignment tll and nhr-168

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001256501.1
• Gene: nhr-168 / 353455
• WormBaseID: WBGene00008221
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 479
• Identity: 94/479 - (19%)
• Similarity: 171/479 - (35%)
• Gaps: 155/479 - (32%)

  Fly     8 PDMMDQKYN-SVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCK 71
            |.::.::.| :.|....|..|......|.:|...::|.||.:.:|:||..||:|.....:.::||
 Worm    23 PSIIQKEPNRTARSESPARQRHQRPSECSICGKTANGYHYDVPSCNGCKTFFRRLCVSEKSFICK 87

  Fly    72 SQKQGLCVVDKTHRN---QCRACRLRKCFEVGMNKDA---------------------------- 105
            :  .|.| .:.|.|.   :|||||..||...|||.:|
 Worm    88 A--GGDC-FNLTKRKVPLKCRACRYEKCISEGMNPNAMLLDEKEATAENFKKLKKRVNQSNPKDP 149

  Fly   106 -------VQHERGPRN-------------------STLRRHMAMYKDAMMGA-----GEMPQIPA 139
                   ::|:...:.                   :.|.|.:..::   |.|     ..:|.:.|
 Worm   150 DDDSGEDIEHQIEKKQVIKDVACIENKMQKLVDMLNYLERKVTKFR---MSAYNPHWSTLPGLEA 211

  Fly   140 EILM-NTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHG 203
            .:|: |..:|....|   ||||.|.:....|                    |::|..
 Worm   212 FLLLENKISLADRSG---PMPGWPLKTQSSP--------------------PKIPEF-------- 245

  Fly   204 FFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEES 268
                           ...||.|..:.:. |......|..::.:.|:...|.:|...|:|:|:.
 Worm   246 ---------------GKKPTGPAYSPDQ-KCWILYDLMVSIEYAKTFMFFHQLDSRDRLVLMR-- 292

  Fly   269 WKEFFILAMAQYLMPMNFAQLLFVYES-ENANREIMGMVTREVHAFQEVLN--QLCHLNIDSTEY 330
                 .:|:|...:.:::..:...|:: .:.:.::..|....|:| :.|::  .|....|..||:
 Worm   293 -----YVALALMNLHISYFTVAKKYDTIIHPDGKLAPMKKGMVYA-ETVMSIAPLIRCEIQETEF 351

  Fly   331 ECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNY 395
            ..|:||.|...:.|      ||                |..::.:|  |:....:.|   ||.::
 Worm   352 VLLKAICLCNPAVP------DL----------------SQHAQEIL--GREREQYAD---ALFDH 389

  Fly   396 IQRTHPSQPMRFQTLLGVVQLMHK 419
            ..|.....|.:|..|:|:|.|:.:
 Worm   390 CLRNRKDGPSQFAELIGMVDLLER 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	30/148 (20%)
		NR_LBD	215..436	CDD:416257	42/208 (20%)
nhr-168	NP_001256501.1	ZnF_C4	50..120	CDD:197701	27/72 (38%)
		HOLI	264..414	CDD:214658	38/185 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840