Protein Alignment tll and hnf4b

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_991109.1
• Gene: hnf4b / 324010
• ZFINID: ZDB-GENE-030131-2730
• Length: 465
• Species: Danio rerio
• Alignment Length: 456
• Identity: 113/456 - (24%)
• Similarity: 180/456 - (39%)
• Gaps: 137/456 - (30%)

  Fly    14 KYNSVRLSPA---------ASSRILYHVP-------CKVCRDHSSGKHYGIYACDGCAGFFKRSI 62
            :::.:|:.|.         ||:.:...||       |.:|.|.::|||||..:||||.|||:||:
Zfish    27 EFDGLRVLPVQTDPLMPGHASASVPVVVPQQSSMSLCAICADRATGKHYGASSCDGCKGFFRRSV 91

  Fly    63 RRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDA 127
            |::..|.|:..:|  |||||..|||||.|||||||..||.|:|||:|| .|.|..|.:
Zfish    92 RKNHAYTCRFSRQ--CVVDKDKRNQCRYCRLRKCFRAGMRKEAVQNER-DRISCRREN------- 146

  Fly   128 MMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRV 192
             .|.|   .:..::||...|.|
Zfish   147 -QGVG---TLTIDVLMQAEAYT------------------------------------------- 164

  Fly   193 PHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELP 257
                 ||      |.:...|..:.::      .:.....:.|:..:.|...|.|.|.:..|.||.
Zfish   165 -----HQ------SLSQNLMRDVGSK------KIAGVGDVCESMKQQLLLLVEWAKRIPEFCELS 212

  Fly   258 MPDQLLLLEESWKEFFILAMAQYLMPMNFAQLL---FVYESENANREIMGMVTREVHAFQEVLNQ 319
            :.|::.||.....|..||.:|:..:|.:...||   |:.....:.:|:..:..|   ..:|::..
Zfish   213 VDDRVALLRAHSAEHLILGVARRSLPYSDIILLGNDFIIPVGGSEQEMSKVAVR---ILEELVRP 274

  Fly   320 LCHLNIDSTEYECLRAISLFRKSPPSASSTEDLA----NSSILTGSGSPNSSASAESRGLLESGK 380
            |..|||..||:.||:.|..|....|.....:.:.    .:.:|.      ..|::|.||
Zfish   275 LKELNITDTEFVCLKTIVFFAPDCPGLQCAQAVRRLRFQAQVLL------DEATSEQRG------ 327

  Fly   381 VAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISD 445
                                     ||..||.::..:..|:...:|:|...:.:|..::..|:.:
Zfish   328 -------------------------RFGELLLLLTTLQSVAWQMLEQLQLMRLLGRASVDSLLME 367

  Fly   446 M 446
            |
Zfish   368 M 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	51/98 (52%)
		NR_LBD	215..436	CDD:416257	45/227 (20%)
hnf4b	NP_991109.1	NR_DBD_HNF4A	63..138	CDD:143518	46/77 (60%)
		NR_LBD_HNF4_like	153..368	CDD:132729	55/314 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910