Protein Alignment tll and Nr1h4

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001157172.1
• Gene: Nr1h4 / 20186
• MGIID: 1352464
• Length: 488
• Species: Mus musculus
• Alignment Length: 406
• Identity: 94/406 - (23%)
• Similarity: 145/406 - (35%)
• Gaps: 89/406 - (21%)

  Fly    19 RLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKT 83
            |::.|::.||.....|.||.|.:||.||....|:||.|||:|||.::..|.||:  .|.||:|..
Mouse   123 RMAAASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKN--GGNCVMDMY 185

  Fly    84 HRNQCRACRLRKCFEVGMNKDAVQ----HERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMN 144
            .|.:|:.||||||.|:||..:.:.    .|...::..||:::..:.|......:.   ....|..
Mouse   186 MRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTANEDDS---EGRDLRQ 247

  Fly   145 TAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLD-----LSVPRVPHHPVHQGHHGF 204
            ..:.|.|              ......:.|.|     ..:||     .:..|:|....::.....
Mouse   248 VTSTTKF--------------CREKTELTADQ-----QTLLDYIMDSYNKQRMPQEITNKILKEE 293

  Fly   205 FSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESW 269
            ||   |..|.|.               :.|.|..|:...|.:.|.:..|..|...||:.||:.|.
Mouse   294 FS---AEENFLI---------------LTEMATSHVQILVEFTKKLPGFQTLDHEDQIALLKGSA 340

  Fly   270 KEFFILAMAQYL---MPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYE 331
            .|...|..|:..   :|...|.||   |.......|.......:.:|.:.:.:   |.:...||.
Mouse   341 VEAMFLRSAEIFNKKLPAGHADLL---EERIRKSGISDEYITPMFSFYKSVGE---LKMTQEEYA 399

  Fly   332 CLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYI 396
            .|.||.:.                             |.:.:.:.:...|..:.......|....
Mouse   400 LLTAIVIL-----------------------------SPDRQYIKDREAVEKLQEPLLDVLQKLC 435

  Fly   397 QRTHPSQPMRFQTLLG 412
            :...|..|..|..|||
Mouse   436 KMYQPENPQHFACLLG 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	38/95 (40%)
		NR_LBD	215..436	CDD:416257	38/201 (19%)
Nr1h4	NP_001157172.1	NR_DBD_FXR	135..222	CDD:143520	36/88 (41%)
		NR_LBD_Fxr	264..483	CDD:132734	47/246 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910