Protein Alignment tll and nhr-74

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_492919.2
• Gene: nhr-74 / 191723
• WormBaseID: WBGene00003664
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 429
• Identity: 79/429 - (18%)
• Similarity: 142/429 - (33%)
• Gaps: 150/429 - (34%)

  Fly    34 CKVCRDHSSGK-HYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCF 97
            |:||:.....: ::||.:|..||.||:||  ...||:|.:...  |.:....:..|||||...|.
 Worm    11 CQVCQSTERTRLYFGITSCAACAAFFRRS--DGIQYMCTANNS--CTIAYDIKFFCRACRYESCV 71

  Fly    98 EVGMNKDAVQHERGPRNSTL-------RRHMAMYKDAMMGAGEMPQIP--------AEILMNTAA 147
            ..||.:|.|:..|..:|...       ..|:.:.....:|:....:..        ::||.||
 Worm    72 RAGMRRDNVRKHRTHQNQAATPGAVIPELHLRLTPTDSLGSSSSSRSTSPDDSEEFSDILDNT-- 134

  Fly   148 LTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYM 212
                                  .|:         :::.||.:  |..|  |:|     |.|.:.:
 Worm   135 ----------------------LHV---------SSITDLMI--VSAH--HEG-----SSTESCL 159

  Fly   213 NALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAM 277
            |.       |...::..|.::.......|.| .||.|:  |..|..|:|:.|::...::     :
 Worm   160 NC-------PGVDMLDKEDVEVLLKYFKFSN-TWIDSI--FASLISPNQVELIQCDHED-----I 209

  Fly   278 AQYLMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKS 342
            |:::               |.::..:|.             .|.|||::..||...::..:::..
 Worm   210 AKFI---------------NHSKSTLGF-------------SLSHLNLNIIEYSVFKSFCIWKLV 246

  Fly   343 PPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRF 407
            ....|....:.......|                           ..|||..|.::......:..
 Worm   247 YHETSIAMKIMAQEHFEG---------------------------VTSALRKYYRKESKMNDLEV 284

  Fly   408 QTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDM 446
            .|.:|.:                  |:..||:..|.:||
 Worm   285 ATRIGDI------------------TLQIITVSNLYNDM 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	28/83 (34%)
		NR_LBD	215..436	CDD:416257	30/220 (14%)
nhr-74	NP_492919.2	ZnF_C4	11..78	CDD:197701	24/70 (34%)
		HOLI	153..301	CDD:214658	35/235 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910