Protein Alignment tll and nhr-245

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001366650.1
• Gene: nhr-245 / 191496
• WormBaseID: WBGene00014189
• Length: 326
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 84/446 - (18%)
• Similarity: 141/446 - (31%)
• Gaps: 178/446 - (39%)

  Fly    34 CKVCRDHSSGK---HYGIYACDGCAGFFKRS--IRRSRQYVCKSQKQGLCVVDKTHRNQCRACRL 93
            |:||  ||:.:   ::||.:|..||.||:||  ||    |:|.:...  |.:....:..|||||.
 Worm    15 CQVC--HSTERTRLYFGITSCAACAAFFRRSDGIR----YMCTATNS--CTISHDMKFFCRACRY 71

  Fly    94 RKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQ--IPAEILMNTAALTGFPGVPM 156
            ..|...|                    |.|.::|:..|.:.|.  ||.|            ..|.
 Worm    72 TSCIRAG--------------------MVMSRNALATARKAPNNIIPRE------------PTPR 104

  Fly   157 PMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALP 221
            .:|.|.:..|.              :.:|::|...:..:.|.:
 Worm   105 SVPSLEEVDGF--------------SKILNISNGDLLKYYVKE---------------------- 133

  Fly   222 PTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTE-------LPMPDQLLLLEE------------ 267
             ...:||.:...|.......|:||.:..|.|:.|       ...|...:|..|
 Worm   134 -VESIMAQQRYGEQKNALQVKSVNDLMIVTAYQEGTSLESCFNCPGVDILYNEDVEVVHKYFKFS 197

  Fly   268 -SWKEFFILAMAQYLMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVL-NQLCHLNIDSTEY 330
             :|.: .:||....|.|             :.|..|    :..:|..:..| :.|..||::..||
 Worm   198 NTWID-SLLAPTSPLDP-------------SCNERI----SEFIHLLKSTLGSTLAQLNLNIIEY 244

  Fly   331 ECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAM--HNDARSALH 393
            ...::..:::......|.                             |.|:.|.  :....|||.
 Worm   245 AAFKSFCIWKLVYHKTSI-----------------------------SMKIVAQEHYEGVTSALR 280

  Fly   394 NYIQRTHPSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITI-VRLISDMYS 448
            .|.::                       :..:.||.....|||||: :..:|::|:
 Worm   281 KYYRK-----------------------NIKMSELEMATRIGDITLQIITVSNLYN 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	26/87 (30%)
		NR_LBD	215..436	CDD:416257	37/243 (15%)
nhr-245	NP_001366650.1	ZnF_C4	15..79	CDD:197701	26/91 (29%)
		HOLI	168..311	CDD:214658	33/212 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910