Protein Alignment tll and Ppara

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001106889.1
• Gene: Ppara / 19013
• MGIID: 104740
• Length: 468
• Species: Mus musculus
• Alignment Length: 513
• Identity: 121/513 - (23%)
• Similarity: 184/513 - (35%)
• Gaps: 158/513 - (30%)

  Fly     2 QSSEGSPDMMDQKY--------NSV---RLSPAASSRIL----------------YHVPCKVCRD 39
            :.|.||....|.:|        .||   .||||:|...:                .::.|::|.|
Mouse    43 EESSGSFGFADYQYLGSCPGSEGSVITDTLSPASSPSSVSCPVIPASTDESPGSALNIECRICGD 107

  Fly    40 HSSGKHYGIYACDGCAGFFKRSIRRSRQY-VCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNK 103
            .:||.|||::||:||.|||:|:||....| .|...    |.:.|.:||:|:.||..||..|||:.
Mouse   108 KASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRS----CKIQKKNRNKCQYCRFHKCLSVGMSH 168

  Fly   104 DAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEIL--------MNTAALTGFPGVPMPMPG 160
            :|::..|.||:                  |..::.||||        ..||.|          ..
Mouse   169 NAIRFGRMPRS------------------EKAKLKAEILTCEHDLKDSETADL----------KS 205

  Fly   161 LPQRAGHHPAHMAAF-QPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNAL--ATRALPP 222
            |.:|.  |.|::..| .....|..:|.......|...:|.            |..|  |.:.|..
Mouse   206 LGKRI--HEAYLKNFNMNKVKARVILAGKTSNNPPFVIHD------------METLCMAEKTLVA 256

  Fly   223 TPPLMAAEHIKETAAEHLF-------------KNVNWIKSVRAFTELPMPDQLLLLEESWKEFFI 274
            .   |.|..:::..||..|             :...:.|::..|..|.:.||:.||:....| .|
Mouse   257 K---MVANGVEDKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYE-AI 317

  Fly   275 LAMAQYLMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLNQLCH--------------LNI 325
            ..|...|  ||...:|..|.:        |.:|||.  .:.:....|.              |.:
Mouse   318 FTMLSSL--MNKDGMLIAYGN--------GFITREF--LKNLRKPFCDIMEPKFDFAMKFNALEL 370

  Fly   326 DSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARS 390
            |.::      ||||              .::|:.....|         |||..|.:..:......
Mouse   371 DDSD------ISLF--------------VAAIICCGDRP---------GLLNIGYIEKLQEGIVH 406

  Fly   391 ALHNYIQRTHPSQPMRFQTLL-GVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDMY 447
            .|..::|..||.....|..|| .:|.|...|:.........:||..|..:..|:.::|
Mouse   407 VLKLHLQSNHPDDTFLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	37/108 (34%)
		NR_LBD	215..436	CDD:416257	52/250 (21%)
Ppara	NP_001106889.1	NR_DBD_Ppar	101..184	CDD:143523	37/104 (36%)
		NR_LBD_PPAR	201..467	CDD:132730	67/333 (20%)
		Required for heterodimerization with RXRA. /evidence=ECO:0000250	304..433		37/170 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910