Protein Alignment tll and nhr-209

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_506036.2
• Gene: nhr-209 / 187663
• WormBaseID: WBGene00011100
• Length: 418
• Species: Caenorhabditis elegans
• Alignment Length: 431
• Identity: 92/431 - (21%)
• Similarity: 158/431 - (36%)
• Gaps: 108/431 - (25%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQ-CRACRLRKCF 97
            |.||::.:.|.||.:.:|:||..||:|:|...::::|.:.|..|..::.....: |:.||..:|.
 Worm    46 CAVCKNAAIGYHYNVPSCNGCKTFFRRTILNGKRFICMNHKNCLDEIESDESQRLCKGCRFARCI 110

  Fly    98 EVGMNKDAVQH-----------ERGPRNSTLRRHMAMYKDAMMG--AGEMPQIPAEI--LMNTAA 147
            ||||:..|::.           |...|....|:.....||..:.  ..::..:..:|  |..:..
 Worm   111 EVGMDSTAIRASVKTVEGKYLLEEVLRKQKNRKIQMQQKDNFLSLIIKQLSHLEDQIEKLHFSTI 175

  Fly   148 LTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPH-HPVHQGHHGFFSPTAAY 211
            ..||.    .|..|.:...::|              |.|.|  |:|: .||..........|  |
 Worm   176 PDGFE----DMRSLSEILLYNP--------------VFDSS--RIPNLTPVSNKAPKLICMT--Y 218

  Fly   212 MNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPM----PDQLLLLEESWKEF 272
            |::....|:..:........|...|...|.::|:.|.|........|    .|:|||.:.:
 Worm   219 MHSALLAAVEASKTFEFFSKISHEARMILIRHVSLIGSNMMSASFSMHHRKSDELLLPDGT---- 279

  Fly   273 FILAMAQYLMPMNFAQLLFVYESENANREIMGMVTREV-------HAFQEVLNQLCHLNIDSTEY 330
                               |:.|      |.|.:..||       :..|::|:....:|:|..||
 Worm   280 -------------------VFGS------IGGCLASEVLGEIKYKNQLQQILHAFLRINVDRVEY 319

  Fly   331 ECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNY 395
            ..|:||.:...|.|..:..:.|                      ::|:.:     |....||..|
 Worm   320 MILKAILMRNPSVPGLTLDDQL----------------------IIENER-----NQYAKALLEY 357

  Fly   396 IQRTHP--SQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTI 434
            ....|.  |.|.||.:|:.:..::...|....:...|.||:
 Worm   358 TILHHGVLSGPARFGSLIAINPIIETQSKKQKDVYVFMKTL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	27/94 (29%)
		NR_LBD	215..436	CDD:416257	45/233 (19%)
nhr-209	NP_506036.2	NR_DBD_HNF4A	46..120	CDD:143518	25/73 (34%)
		HOLI	219..384	CDD:214658	42/220 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840