Protein Alignment tll and nhr-208

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_506034.2
• Gene: nhr-208 / 187662
• WormBaseID: WBGene00011099
• Length: 410
• Species: Caenorhabditis elegans
• Alignment Length: 480
• Identity: 98/480 - (20%)
• Similarity: 184/480 - (38%)
• Gaps: 127/480 - (26%)

  Fly     9 DMMDQKYNSVRLSPAASSRILYH-VP--CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVC 70
            |...|:.:|..:..:.|.:...| :|  |::|.:.:.|.||.|.:|:||..||:|::...||..|
 Worm    15 DQRSQESSSYSILTSTSIKCPRHNLPSKCEICGNPAIGYHYDIASCNGCKAFFRRTVITGRQVAC 79

  Fly    71 KSQKQGLCVVDK--THRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDA---MMG 130
            |  |.|.|:.::  .:|..|..||..||.:||||..|::.|.......|:..:...::|   :|.
 Worm    80 K--KWGTCLEEEIPINRRICPGCRFSKCVKVGMNPRAIRAEISSNGEILKNQLLKNREADKLVML 142

  Fly   131 AGEMPQIPAEILMNTAAL----------TGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVL 185
            :.:..:....|.::..:|          :.:|........:.:....||              :|
 Worm   143 SPKTAEDDLSISISKLSLIENKIDDLFNSKWPSNYCDWRTVTEILKAHP--------------IL 193

  Fly   186 DLS-VPRVPHHP--VHQGHHGFFSPTAAYMNALA----TRALPPTPPLMAAEHIKETAAEHLFKN 243
            ::| :|.:...|  :...|.||     |:..:||    |:.|...|.| :.:.:::.....||..
 Worm   194 EMSKIPNLSFQPNQLFPDHAGF-----AHNASLAALEFTKMLDIFPKL-SIDTVQKLVRHGLFMC 252

  Fly   244 VNWIKSVRAFTELPMPDQLLLLE--------ESWKEFFILAMAQYLMPMNFAQLLFVYESENANR 300
            .:.:.|.|:..:. ..|.|...:        :||...::                       .:|
 Worm   253 GSMMTSRRSIQKF-NSDTLRRTDGTISGKPAKSWNGVWV-----------------------DHR 293

  Fly   301 EIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPN 365
            :|:          |.||.....:.::..||..|:.|::..   |:.|   ||
 Worm   294 KIV----------QRVLRAFLRIKLNDVEYLFLKVITILN---PAVS---DL------------- 329

  Fly   366 SSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQ--PMRFQTLLGVVQLMH----KVSSFT 424
               .|:.:.::|..:     |.....|..|..|.:...  |.||.::|.::..|.    :..||.
 Worm   330 ---FAQDQKIIERER-----NRFAQCLLTYCLREYAENNGPSRFASVLSIISSMELQQKEEKSFN 386

  Fly   425 IEELFFRKTIGDITIVRLISDMYSQ 449
            |   ..|.:..|..:  |:|.::.:
 Worm   387 I---LLRASFPDAIV--LVSPLFDE 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	34/96 (35%)
		NR_LBD	215..436	CDD:416257	42/238 (18%)
nhr-208	NP_506034.2	ZnF_C4	42..112	CDD:197701	28/71 (39%)
		HOLI	216..376	CDD:214658	38/221 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840