Protein Alignment tll and nhr-37

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_504683.1
• Gene: nhr-37 / 185727
• WormBaseID: WBGene00018412
• Length: 417
• Species: Caenorhabditis elegans
• Alignment Length: 457
• Identity: 96/457 - (21%)
• Similarity: 154/457 - (33%)
• Gaps: 124/457 - (27%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFE 98
            |.||:..|:|.|:|...|..||.||:|:.....||.|| |....|.:|...|..||.|||.||..
 Worm     7 CLVCKKASNGMHFGALTCRACAAFFRRATVLKLQYKCK-QGNSKCNIDGRGRYVCRQCRLTKCKA 70

  Fly    99 VGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAG----EMPQIPAEILMNTAALTGFPGVPMPMP 159
            :|||::.||.:..|..|        ::..|..:|    ..|.
 Worm    71 IGMNEEKVQLDYDPTYS--------FRGLMEDSGSDEFSTPN----------------------- 104

  Fly   160 GLPQRAGHHPAHMA---AFQPPPSAAAVLDLSVPRVPHHP---------VHQGHHGFFSPTAAYM 212
            |.|.::.:.|.:::   :.:.|......|....|:.|..|         |.:....|...|....
 Worm   105 GSPAQSDYSPTNLSRKNSVESPGIDPNFLFTFSPKTPDKPNMVISFNDLVKKIETSFSHKTKGDD 169

  Fly   213 NALAT---------RALPPTPPLMAAEHIKETAA-----EHLFKNVNWIKSVRAFTELPMPDQLL 263
            ..|.|         :.......:...:.::..:|     :.::....|..|.::...|||..::.
 Worm   170 CELTTLTSALKKFRKNQKAQSQISFLDKVELKSAIDWLNDRIYMYSCWFSSSKSLMSLPMDQKMQ 234

  Fly   264 LLEESW-------------KEF--------FILAMAQYLMPMNFAQLLFVYESENANREIMGMVT 307
            |...||             |.|        :||......|.:....:.|...::..|:
 Worm   235 LFRSSWNVVRTFERLEMSVKIFEEGVIRGGYILINDDLAMKLESTHIDFASITDLTNQ------- 292

  Fly   308 REVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAES 372
                .|.::.....|..||..      |..|....|    :||::....:.. .|......|.|:
 Worm   293 ----YFNKLFEPFLHRYIDEV------ARPLLDLKP----TTEEVVFCMVHL-IGLEEGDLSHET 342

  Fly   373 RGLLESGKVAAMHNDARSALH-NYIQRT------HPSQPMRFQTLLGVVQLMHKVS--SFTIEEL 428
            |...|.     |..:....:| .|..||      |     |...|:.:|:.|.::|  ...|:||
 Worm   343 REACEQ-----MRAEIADQMHVYYTNRTDIKMYSH-----RLLILMKLVKSMKRISREKSKIKEL 397

  Fly   429 FF 430
            |:
 Worm   398 FW 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	35/82 (43%)
		NR_LBD	215..436	CDD:416257	47/260 (18%)
nhr-37	NP_504683.1	ZnF_C4	7..76	CDD:197701	31/69 (45%)
		Hormone_recep	189..393	CDD:278530	41/235 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910