Protein Alignment tll and nhr-1

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001024853.1
• Gene: nhr-1 / 181783
• WormBaseID: WBGene00003600
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 378
• Identity: 91/378 - (24%)
• Similarity: 139/378 - (36%)
• Gaps: 71/378 - (18%)

  Fly     4 SEGSPDM-MDQKYNSVRLSPAASSRILYHVP----CKVCRDHSSGKHYGIYACDGCAGFFKRSIR 63
            :.||..| .|||:.|.:  ..|..|   .||    |.||.|.::|.|||:.:|:||..||:|:|.
 Worm    43 TNGSSSMGNDQKFPSYK--RMAQRR---KVPEGELCAVCSDLATGYHYGVASCNGCKTFFRRTIV 102

  Fly    64 RSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAM 128
            ..:.::|  |..|.|.|:|..|..||.||..||..|||:..|:|.   |.....|..:...|...
 Worm   103 SEQTFIC--QYNGNCDVNKNIRCACRHCRFNKCLLVGMDAKALQI---PAIQNDRDRIGPTKKIK 162

  Fly   129 MGAG---EMPQIP-----AEILMNTAALTGFPGVPMPMPG--LPQRAGHHPAHMAAFQPPPSAAA 183
            |.:|   |....|     .||:   ..||...|:...:..  :|:..|  ..|  |...|.....
 Worm   163 MSSGSDDEQATTPHRLQDQEII---DQLTQVEGLCQELRRCIIPEVTG--VTH--ALTSPCLLFE 220

  Fly   184 VLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIK 248
            ..||.|                  ..:..|.:.....|.:...:...:|:|...     .:.|.|
 Worm   221 TTDLKV------------------DVSLTNTIFKELFPASMNDIRMWNIREMRI-----CIEWAK 262

  Fly   249 SVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMP------MNFAQLLFVYESENANREIMG--- 304
            :...:..|.:.||..|:......|.:|....| .|      :.|....|:........::.|
 Worm   263 TFDVYQRLNLFDQFALVRNFAFAFNLLNRVFY-SPDHGPDKIVFQNGAFIMRQPQQQVQLSGCRP 326

  Fly   305 MVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSI 357
            :.||::   .|::.....|.:...|:...:|...|.   |.|......|...:
 Worm   327 IYTRQM---DEIMIPFRKLQLSVAEFATFKAALFFN---PDALDLSPQAKQEV 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	37/95 (39%)
		NR_LBD	215..436	CDD:416257	26/152 (17%)
nhr-1	NP_001024853.1	NR_DBD_HNF4A	73..153	CDD:143518	34/84 (40%)
		HOLI	252..414	CDD:214658	24/134 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910