DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and sex-1

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001024662.1	Gene:	sex-1 / 181231	WormBaseID:	WBGene00004786	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	137	Identity:	48/137 - (35%)
Similarity:	70/137 - (51%)	Gaps:	32/137 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSEGSPDMMDQKYNSVRLSPAASSRILYHVP-----CKVCRDHSSGKHYGIYACDGCAGFFKRSI 62
            ||...||.:...:.:.|          :|:.     ||||.|.:||.|||:.:|:||.|||:|||
Worm   125 SSLSPPDSLSNGHTTQR----------HHIGKAISFCKVCGDKASGYHYGVTSCEGCKGFFRRSI 179

  Fly    63 RRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHER---------------GP 112
            :|...|.|  .||.:|.:.:..||:|:.||.:||.:.||:||:|:..:               .|
Worm   180 QRKIDYRC--LKQQVCEIKRESRNRCQYCRFKKCLDSGMSKDSVRQMKFRNAMRDDKSPDSVFVP 242

  Fly   113 RNSTLRR 119
            ..|||.|
Worm   243 EISTLER 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	40/111 (36%)
tll	NP_524596.1	NR_LBD	215..436	CDD:416257
sex-1	NP_001024662.1	NR_DBD_DmE78_like	151..231	CDD:143539	37/81 (46%)
sex-1	NP_001024662.1	NR_LBD_Sex_1_like	296..488	CDD:132740
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910