Protein Alignment tll and nhr-14

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_741860.2
• Gene: nhr-14 / 181102
• WormBaseID: WBGene00003613
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 113/433 - (26%)
• Similarity: 172/433 - (39%)
• Gaps: 106/433 - (24%)

  Fly    17 SVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVD 81
            |..||.:.|:...:   |.||.|.:.|||||..||:||.|||:||:.::.||.|:..||  |.:|
 Worm     6 STSLSESTSTSADF---CVVCGDKAIGKHYGAVACNGCKGFFRRSVWQNLQYTCRFNKQ--CNID 65

  Fly    82 KTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTA 146
            |.|||.||.||.:||...||..:|:|:||....||.||..:       ||.......:|
 Worm    66 KDHRNACRYCRFQKCLADGMKPEAIQNERDRIGSTKRRKRS-------GANSENNSDSE------ 117

  Fly   147 ALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAY 211
                  |.|.|                       ...|:..||.|.....:....|...|..:
 Worm   118 ------GTPSP-----------------------KIEVMGNSVSRKLIEMLLDIEHRLASNQS-- 151

  Fly   212 MNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFIL- 275
            ||||          |.....:|.:....:...:.|...:....|:|:.|::|||::....|.:|
 Worm   152 MNAL----------LRDESEMKNSRQRAVNYLIGWTNMLHPLPEVPLADKVLLLKKFSSAFTLLG 206

  Fly   276 ------AMAQYLMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLR 334
                  |:..:::|.:  |:|.:  |.:...|:...:||.:   .|:|..|..|..|..|:.||:
 Worm   207 TLQRSMALPHFVLPND--QVLSI--SASHPPELFEALTRII---DELLTPLRRLRTDHAEFSCLK 264

  Fly   335 AISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRT 399
            |:.|....               :.|..:.......|:|..|.....|.|.|...|.
 Worm   265 ALLLLNPD---------------VVGISNNTRERIREARDALLKTLFAYMSNTQNSI-------- 306

  Fly   400 HPSQPMRFQTLLGVVQLMHKVSSFTIE-----ELFFRKTIGDI 437
              ...:|..:||.::..:..|||..:|     :||   .:||:
 Worm   307 --DASLRVSSLLMIIPSLISVSSSIMEFPALSDLF---GLGDV 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	43/91 (47%)
		NR_LBD	215..436	CDD:416257	47/232 (20%)
nhr-14	NP_741860.2	NR_DBD_HNF4A	20..95	CDD:143518	40/76 (53%)
		HOLI	176..322	CDD:214658	38/177 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910