Protein Alignment tll and nhr-45

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_508797.3
• Gene: nhr-45 / 180738
• WormBaseID: WBGene00003635
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 108/544 - (19%)
• Similarity: 174/544 - (31%)
• Gaps: 183/544 - (33%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFE 98
            |.||...:.|:|:||..|..||.||:|::..:.:|.|:..::  |.|....|..||.||..||..
 Worm     3 CLVCETDAHGQHFGIRCCRACAAFFRRTLTMNLRYKCRFDRK--CEVSFNKRYSCRCCRYEKCVR 65

  Fly    99 VGMNKDAV----------------------------------------------QHERGP----- 112
            |||.||.:                                              |..:.|
 Worm    66 VGMRKDNLTSPVSVVQNKSETEKDSSGNETDSIGHSPHSSLESYTCRPPSFEQQQQNQNPDPPLL 130

  Fly   113 --RNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAF 175
              .|.|..:.:|  .||.....:|.|:  ....:...:.......||.|...|    .|.|:
 Worm   131 MGNNGTFVQEVA--SDAYQPNSDMHQL--NFSFHRTVIEEVGRAVMPTPPFQQ----PPIHI--- 184

  Fly   176 QPPPSAAAVLDL---------SVP-------RVPH---------------------HPVHQGHHG 203
             |.|......||         ::|       :||.                     ..:|.....
 Worm   185 -PQPFDYQYTDLLSTDEQNSSAIPSSFTQYNQVPQEYNNESGNQNQMFAMAAQQATQDLHVNVQN 248

  Fly   204 FFSPTAAYMNALATRA---LPPTP------PLMA-AEHIKE-TAAEHLFKNV-----NWIK---- 248
            ..:||...|......|   ||..|      .|:| .||.|: ...:.:.:||     |:::
 Worm   249 VLTPTIDAMFGQPPDAFCQLPDIPLTLCQQALLAYREHNKQWPDQDKMIENVPLDMENFMRNHYI 313

  Fly   249 ----------SVRAFTELPMPDQLLLLEESWKEFFIL----AMAQYL--------------MPMN 285
                      |:|.|.:||...:.::.:..|..|:.|    |..|.|              ..:|
 Worm   314 EIEHIARFCMSIRVFAQLPKDQKWIIFKHFWTRFYELDRCFATCQRLGYNLTDERGLTLNGQIIN 378

  Fly   286 FAQLLFVYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTE 350
            |.  :.|.:.||    |..|...:|..|.:          .|.:...|..|:.|:|..|:.....
 Worm   379 FG--ISVVKLEN----ISDMDATQVRNFLK----------GSMDKFRLIFINPFKKLQPTEYELM 427

  Fly   351 DLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSA--LHNY----IQRTHPSQPMRFQT 409
            .:..|.:.:.|..|         |:.::.:..:...:.|.|  ||.|    ....:|:...|...
 Worm   428 YMMMSIMWSVSNLP---------GITDATRDISEKVELRLAEDLHTYYAEQYDNNNPNYAGRITR 483

  Fly   410 LLGVVQLMHKVSSFTIEELFFRKT 433
            |..:...:.:::....|:....||
 Worm   484 LSSIASAVDEITERKREDSQVSKT 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	32/135 (24%)
		NR_LBD	215..436	CDD:416257	53/273 (19%)
nhr-45	NP_508797.3	ZnF_C4	3..71	CDD:197701	27/69 (39%)
		NR_LBD	305..494	CDD:132726	39/213 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910