Protein Alignment tll and nhr-18

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_503608.2
• Gene: nhr-18 / 178702
• WormBaseID: WBGene00003617
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 468
• Identity: 89/468 - (19%)
• Similarity: 167/468 - (35%)
• Gaps: 144/468 - (30%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIR-RSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCF 97
            |:||.|.:||:|:|:.:|..||.||:|:.. ...:.:|.:   |.|......:..|:.|||:||.
 Worm    11 CEVCGDKTSGRHFGVMSCRACAAFFRRAATWNLEKRICPN---GTCHTSVNGKFNCKQCRLKKCL 72

  Fly    98 EVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLP 162
            :|||:....|.:|.                ::....:.|          :|..|.|
 Worm    73 DVGMDTRRFQTDRD----------------LISCSAISQ----------SLATFLG--------- 102

  Fly   163 QRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLM 227
                 .|..:...:|..::.....:.|.|:                   :|........||..::
 Worm   103 -----RPEFILCCEPDRASVLKTTIDVTRL-------------------VNIARDMLQKPTNHVL 143

  Fly   228 AAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLE--ESWKEFFILAMAQYLMPMNFAQLL 290
            .:..:     |.|...::.::.|.:..|:...::...:|  :||::.|:..:..:   .||::..
 Worm   144 PSNSL-----EQLATTLDNMRCVESNKEVKFIEKYGKVETLKSWEQGFLRVVEWF---SNFSEFR 200

  Fly   291 FVYE--------------------SENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYE---C 332
            .:.|                    ||.||::|..|:.:.    |.::.....:|:::.|.:   |
 Worm   201 ELNERLKLEIVKSCWFSWTRLDKLSETANKQINKMLGKS----QLMVGNGACMNMNNFEIDLSWC 261

  Fly   333 ----LRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALH 393
                |..:..|.::|....:.:......|.....|...|.......|..:||  .:|.||..|..
 Worm   262 TNYSLEQLKYFFQTPNGKKNFQQSIQDMIDLNPSSIEVSYMLLHLSLEHAGK--RLHGDALDATE 324

  Fly   394 NYIQRTHPSQPMRFQTLLGVVQL--MHKVSSFTIEEL--------------FFRKTIGDITI--- 439
            |.:|                ||.  :||   :.:|:|              ..|....||.|
 Worm   325 NLVQ----------------VQANNLHK---YYVEKLKLANYSSRLTQLMRITRTLEADIRIRIE 370

  Fly   440 VRLISDMYSQRKI 452
            .:.|:|:::..||
 Worm   371 KKQIADVFNIMKI 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	28/83 (34%)
		NR_LBD	215..436	CDD:416257	45/265 (17%)
nhr-18	NP_503608.2	NR_DBD_like	11..86	CDD:295381	27/77 (35%)
		Hormone_recep	163..371	CDD:278530	43/235 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910