DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tll and nhr-43

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_502254.1	Gene:	nhr-43 / 178121	WormBaseID:	WBGene00003633	Length:	449	Species:	Caenorhabditis elegans

Alignment Length:	130	Identity:	39/130 - (30%)
Similarity:	62/130 - (47%)	Gaps:	22/130 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQSSEGSPDMMDQKYNSVRLSPAASSRILYHVPCKVC-RDHSSGKHYGIYACDGCAGFFKRSIRR 64
            :.||..||.:.|..                ::.|:|| |.:...:|:||..|..||.||:||:..
Worm    30 LPSSSSSPTVADPS----------------NIHCRVCERRYDGSQHFGIDICRACAAFFRRSVAV 78

  Fly    65 SRQYVCK--SQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRN-STLRRHMAMYKD 126
            .:.:||:  :.|..|..|.:  :..|:.||..:|..||:|.|||...|.|.: .|..|..::.|:
Worm    79 KKTFVCRRGTNKCELNTVSR--KTTCQKCRWMRCLLVGLNVDAVVGRRSPDHVKTTSRDESVKKE 141

Fly 127 126
Worm 142 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	31/95 (33%)
tll	NP_524596.1	NR_LBD	215..436	CDD:416257
nhr-43	NP_502254.1	ZnF_C4	47..118	CDD:197701	26/72 (36%)
nhr-43	NP_502254.1	Hormone_recep	231..428	CDD:278530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910