Protein Alignment tll and nhr-4

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_501775.1
• Gene: nhr-4 / 177839
• WormBaseID: WBGene00003603
• Length: 492
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 126/513 - (24%)
• Similarity: 188/513 - (36%)
• Gaps: 186/513 - (36%)

  Fly    12 DQKYNSVRLSPAASS---------RILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQ 67
            |.||:....||:.|:         |::    |.||.|.:.||||||.||:||.|||:||:...||
 Worm    23 DYKYDGADTSPSTSNGLPETSNGGRLI----CDVCGDVAFGKHYGINACNGCKGFFRRSVWSRRQ 83

  Fly    68 YVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHER----------GPRNSTLRRHMA 122
            |.|:.  .|.|.|.|.|||.||:|||:||||||||.|:||:||          ||.:|..:  .:
 Worm    84 YSCRF--GGDCPVVKEHRNVCRSCRLKKCFEVGMNPDSVQNERDRNAKNGGMGGPMSSPTQ--SS 144

  Fly   123 MYKDAMMGAGEM--PQIPAEILMNTAALTG---------FPGV---PMPMPGLPQRAGHHPAHMA 173
            :.|:..:..|::  .::..|.:..|....|         |..:   |.| |||      .|..:.
 Worm   145 LCKELTISNGQIKRKRLRPETVEKTTQTDGKLEINDDFDFENMQQNPTP-PGL------LPLKIE 202

  Fly   174 AFQPPPSAAAVLDLSVPRVPHHPVHQG-----HHGFFSPTAAYMNALATRALPPTPP-------- 225
            ....|||     ||.||.  ...:|..     ...|::...|..|::.....|.|.|
 Worm   203 RISTPPS-----DLPVPM--DFSIHSAVLDIEQKVFYNCPVAVDNSINATKTPITLPFEVVFRQP 260

  Fly   226 ---------------LMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEE-------- 267
                           ::..|.:.:....|.....:|..::..|..|...||::|.::
 Worm   261 HLVCNRYPMRFSNTRVLTPEDLIDGWRRHFTYYSDWCHAMDEFKALSPEDQIVLAKKKIILHGWL 325

  Fly   268 -----SWK------------------------EFFILAMAQYLMPMNFAQLLFVYESENANREIM 303
                 |:|                        ||:...|.:||   |:
 Worm   326 VHAYYSYKSGCNGICFANGAAHLPEGGHPSITEFYKECMPRYL---NY----------------- 370

  Fly   304 GMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSA 368
              |...:|.||          :|..|...::.|..|
 Worm   371 --VIYPMHNFQ----------MDDAEMVLIKCIMFF----------------------------- 394

  Fly   369 SAESRGLLESGK--VAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMHKVSSFT 424
            |:|| ||..:|:  |:|......|||:||.:....:...  |..|.:.:.|..:|:.|
 Worm   395 SSES-GLSAAGRQIVSAAREKYLSALYNYGRANKCTTSA--QATLRIAKFMIMLSAIT 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	53/110 (48%)
		NR_LBD	215..436	CDD:416257	45/272 (17%)
nhr-4	NP_501775.1	NR_DBD_HNF4A	50..125	CDD:143518	47/76 (62%)
		NR_LBD	280..451	CDD:132726	42/234 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910