Protein Alignment tll and nhr-19

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_496066.2
• Gene: nhr-19 / 174512
• WormBaseID: WBGene00003618
• Length: 477
• Species: Caenorhabditis elegans
• Alignment Length: 460
• Identity: 106/460 - (23%)
• Similarity: 158/460 - (34%)
• Gaps: 127/460 - (27%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFE 98
            |.:|.:.|:||||||.||.||..||:|::.:.:...||.:|.  |.|....|..|||||.|||.|
 Worm    80 CLICGEPSTGKHYGIVACLGCKTFFRRAVVQRQDTECKREKP--CDVTTMARKACRACRYRKCLE 142

  Fly    99 VGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMP------ 157
            .||:|:|:|    ||..            ::|...:...|       :..|..|..|.|
 Worm   143 SGMSKEALQ----PRRD------------LIGCRRIRSRP-------SCSTSTPTPPRPQVEDKS 184

  Fly   158 --------MPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNA 214
                    :..:..|.......:.|     |..|.:||:|         ....|..|.|.. ...
 Worm   185 QYLTLLENLTTIDDRLRKKKLEVVA-----SRQAAVDLAV---------LAKQGCMSITDT-SGP 234

  Fly   215 LATRALP-PTPP--------LMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWK 270
            ..:|.:| .|.|        :|....|..:....|...:.|.:::..|..||:.|:.::|:....
 Worm   235 STSRYVPGGTSPNGGDHKMMVMLGTDISVSTQSELLMMLEWTRTLPVFASLPVQDRSVILKRFAV 299

  Fly   271 EFFILAMAQY----------------LMPMNFAQL-----LFVYESENANREIMGMVTREVHAFQ 314
            ...||....|                .||.|..:|     :.|.......:|.:.....:. ...
 Worm   300 HCLILEHGYYTAQANIDDVWLITNGTCMPRNVEKLEEGCKISVSADRRWRQEKLYKQMTDC-CID 363

  Fly   315 EVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESG 379
            ||...|.:|.:...|...::.|.||.                  .|..|..|..:..||.:
 Worm   364 EVATPLRNLKLSPQEIVVIKIIVLFN------------------CGCSSDYSEITEASRRI---- 406

  Fly   380 KVAAMHNDARSALHNYIQRTH-PSQPMRFQTLL----GV------------VQLMHKVSSF--TI 425
             |....|...|||..|.:... .:...||..|:    ||            |..:.|::.|  ..
 Worm   407 -VLTFRNKVVSALFAYYESVGLQNYAERFGNLVLMLSGVSSAASSMLEAYQVMRLFKITPFDPLS 470

  Fly   426 EELFF 430
            :||.|
 Worm   471 QELLF 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	38/82 (46%)
		NR_LBD	215..436	CDD:416257	52/265 (20%)
nhr-19	NP_496066.2	NR_DBD_HNF4A	80..155	CDD:143518	38/80 (48%)
		HOLI	268..447	CDD:214658	40/202 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910