Protein Alignment tll and nhr-21

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_001040766.1
• Gene: nhr-21 / 174202
• WormBaseID: WBGene00003620
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 296
• Identity: 82/296 - (27%)
• Similarity: 124/296 - (41%)
• Gaps: 83/296 - (28%)

  Fly    16 NSVRLSPAASSRILY--H---VPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQ 75
            :::||....||:.|.  |   :.|.||.|.:.|||||:.||:||.|||:|||.::|.|.|:  .|
 Worm     7 STMRLMSKDSSQSLVANHKATLFCAVCGDTALGKHYGVTACNGCKGFFRRSIWKNRTYACR--YQ 69

  Fly    76 GLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHE--------RGPRNSTLRRHMAMYKDAMMGAG 132
            |.|.|.|..||.||:|||::|.:||||..|||.:        ..|...::..|.....:.:
 Worm    70 GKCGVAKEQRNACRSCRLKECIKVGMNPRAVQGDIDTASTSSASPNLVSVEMHPYTKSEEV---- 130

  Fly   133 EMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPV 197
                   |.....:.::..|..|..:|.:                 .|.:::..:|
 Worm   131 -------ECQTEVSTISSHPTSPSTLPFV-----------------SSGSSICSVS--------- 162

  Fly   198 HQGHHGFFSPTAAYMNALATRALPPTPP------LMAA---------EHIKET-----AAEHLFK 242
                ....|.:..|.|.||  .|||.|.      |:|:         ||..|.     :.||.|.
 Worm   163 ----SSCSSVSTVYSNCLA--MLPPNPSLPKYDYLLASLSRIFERVDEHAPEPLPNTYSFEHAFY 221

  Fly   243 NVNWIKSVRAFTELPMPDQLLLLEESWKEF---FIL 275
            |.:.|.:....|  |..:::..|.|..::|   |:|
 Worm   222 NPHLICNRTKLT--PTGERIATLPEVLQDFRRIFVL 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	47/104 (45%)
		NR_LBD	215..436	CDD:416257	23/84 (27%)
nhr-21	NP_001040766.1	NR_DBD_HNF4A	30..105	CDD:143518	42/76 (55%)
		NR_LBD	244..416	CDD:132726	4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910