Protein Alignment tll and nhr-22

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_495298.1
• Gene: nhr-22 / 174066
• WormBaseID: WBGene00003621
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 117/566 - (20%)
• Similarity: 186/566 - (32%)
• Gaps: 176/566 - (31%)

  Fly     5 EGS----------PDMMDQKYNSVR--LSPAASSRILYHVPCKVCRDHSSGK-HYGIYACDGCAG 56
            |||          |:::::...|.|  .||...||     .|.||...::.. |:|..:|..||.
 Worm    60 EGSSSPPPESNHLPEIVNKASTSPRGMPSPLTDSR-----SCHVCSSPTANTLHFGGRSCKACAA 119

  Fly    57 FFKRSIRRSRQYVC--KSQKQGLCVVDKTH---RNQCRACRLRKCFEVGMNKDAVQHERGPRNST 116
            ||:||:..|..|.|  .......|   :||   |..||.||..||.:.||.::.||..:......
 Worm   120 FFRRSVSMSMTYECIGTGDDTNPC---RTHYELRMICRHCRFIKCLDAGMRRELVQARKEETRVA 181

  Fly   117 LRRHMAMYKDAMMGAGEMPQIPA--EILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPP 179
            .||.    |..::...|...:.:  :..:||     :..|....|.:...........:...|.|
 Worm   182 KRRS----KGLVVSKKEDDDVESSYDEYVNT-----YTNVQDSSPKMESGINEMTIPESYLSPDP 237

  Fly   180 SAAAVLDLSVPRVPHH----------------------------PVHQ---GHHGF-----FSPT 208
            |::..||::|...|.|                            .:||   .|.||     |.|.
 Worm   238 SSSQPLDMTVTPPPLHRSTPSILLTPATGDRMHCQRVLSNSPPFDIHQASTSHAGFIQHVQFYPV 302

  Fly   209 AAYMNAL---------ATRALPPTPPLMAAE----HIKETAAE-----HLFKNVNWIKSVRAFTE 255
            ....|.:         ...:|.....:|..:    .:.:|..|     |..|..|:    ::|..
 Worm   303 VEVENKIFELVDHYVRTEASLNDRRKIMYTDTQIRDVFDTTCECPYENHQLKPFNY----KSFCG 363

  Fly   256 LPMPDQLLLLE--ESWKEF-------------------FILAMAQYLMPMNFAQ---LLFVYESE 296
            ....|.:::|:  ..:.||                   .:||.|.|...:...:   :||..:..
 Worm   364 FVKHDFVMILDYVNQFPEFQALHKNDKNVVYRMACAVDSMLASAYYSYKVGIEKERLILFNGDYI 428

  Fly   297 NANR-EIMG--------MVTREVHAFQEVLNQL------------CHLNIDSTEYECLRAISLFR 340
            |.|. .|.|        ..|.:.|...:.|..|            ..|.:...||..|:|:.:::
 Worm   429 NMNPIPISGDEPGAGTEFQTPQEHEKYKTLMPLKLKQYFDLAIPFARLEVSFEEYVLLKALIIWQ 493

  Fly   341 KSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGK-VAAMHNDA-RSALHNYIQRTHPSQ 403
            .|                             :..|||.|: :.|...|. ..|||..::......
 Worm   494 IS-----------------------------NYRLLEEGRAICARQRDTIVQALHKVVEERGDED 529

  Fly   404 P-MRF-QTLLGVVQLMHKVSSFTIEEL---FFRKTIGDITIVRLIS 444
            | :|. |.||.:..:..:|.:.|...|   ||.....|..:..|:|
 Worm   530 PAIRVGQLLLSMSYITEQVQAMTNSYLVMTFFDVVSCDSIMYDLLS 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	31/97 (32%)
		NR_LBD	215..436	CDD:416257	51/290 (18%)
nhr-22	NP_495298.1	ZnF_C4	96..169	CDD:197701	27/75 (36%)
		HOLI	366..547	CDD:214658	38/209 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910