Protein Alignment tll and nhr-69

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_492615.2
• Gene: nhr-69 / 172840
• WormBaseID: WBGene00003659
• Length: 373
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 106/427 - (24%)
• Similarity: 167/427 - (39%)
• Gaps: 124/427 - (29%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFE 98
            |.:|.|.|:|||||..:||||.|||:||||:...|.|:.::.  |.|.|..||.||||||:||.:
 Worm     6 CHICNDKSTGKHYGAISCDGCKGFFRRSIRKRYHYQCRFEQN--CDVTKNKRNACRACRLQKCVK 68

  Fly    99 VGMNKDAVQHER---GPRNSTLRRHMAMYKDAMMGAGEM-PQIPAEILMNTAALTGFPGVPMPMP 159
            .||..:|:|:||   |.|..|.........|.::.|..: .|:.:.::.||::|.
 Worm    69 AGMKSNAIQNERDAIGKRKKTTGAEKEDLIDQLVAAETLCQQLRSSVIKNTSSLA---------- 123

  Fly   160 GLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTP 224
              |...|     ...:....:.||.||
 Worm   124 --PYDCG-----KVKWNYEDARAATLD-------------------------------------- 143

  Fly   225 PLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQL 289
                  .|.::..:.|...:.|.||:..|:.|...||..||:.......:|.:|       :..:
 Worm   144 ------DIGKSIHQQLVLFIEWAKSLPQFSFLAQADQAALLKGGAASIIVLGVA-------YRSI 195

  Fly   290 LFVYES------------ENANR--EIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFR 340
            ....|:            |:|.:  :|..:|.|.:   .|::|.:..||:|..||..|:||..|.
 Worm   196 CLTVENTICLANDTLLPKEHATQVGDINCVVGRII---DEIVNPMRRLNMDLIEYVALKAILFFN 257

  Fly   341 --------KSPP---------------SASSTEDLANSSILTGSGS-----PNSSASAESRGLLE 377
                    :||.               :..:.|::.:.|:...||.     |:..|.|:.  |:|
 Worm   258 PVVREINDQSPVENARYAFLRSLQRRCTDKALENMEDESMDCRSGKLLLLLPSLQAIAQQ--LVE 320

  Fly   378 SGKVAAMHN--DARSALHNYI-QRTHPSQPMRFQTLL 411
            ..::|.:..  :..|.:...| ....||.|...||.|
 Worm   321 DVQLARLFGLVNVDSLMEELILNDMKPSDPQILQTSL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	43/85 (51%)
		NR_LBD	215..436	CDD:416257	50/242 (21%)
nhr-69	NP_492615.2	NR_DBD_HNF4A	6..81	CDD:143518	40/76 (53%)
		NR_LBD	98..340	CDD:299703	55/314 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840