Protein Alignment tll and nhr-62

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_492607.1
• Gene: nhr-62 / 172836
• WormBaseID: WBGene00003652
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 103/440 - (23%)
• Similarity: 183/440 - (41%)
• Gaps: 80/440 - (18%)

  Fly    34 CKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFE 98
            |.||.|.:.|||||:.||:||.|||:||:..:|||:|:.  :|.|.:.|.|||.||||||::||.
 Worm    98 CVVCGDQAFGKHYGVNACNGCKGFFRRSVWHNRQYLCRF--EGRCAIAKEHRNVCRACRLKQCFV 160

  Fly    99 VGMNKDAVQHERGPR---NSTLRRHMAMYKDAMMGAGEMPQIPAEI------LMNTAALTGFPGV 154
            .|||..|||.||..|   .|..:.....|||.........:|..::      ..|:|.|   |.:
 Worm   161 AGMNPRAVQSERVEREQNGSPNQIEEDDYKDLSSPDTCSVEIQTDVDEQKPSSNNSAPL---PSM 222

  Fly   155 PMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALAT-R 218
            .:.|..|.::.......:.::..|.:.....|:.:...             :...|:|||... .
 Worm   223 ELEMAKLSEQIVEMHRAVCSYVDPVTKRENFDMKMETE-------------TTKIAFMNAFYNPE 274

  Fly   219 ALPPTPPL----MAAEHIKETAAEH-----LFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFI 274
            .:.|..||    .....:|:...|.     ||.  :|::::..:.::.:.||::|.:..:..|..
 Worm   275 MIGPRTPLDITGRRVATVKDVMDEWKRNFVLFS--DWLRALPEYNQMSIEDQIVLAKNRYGTFHW 337

  Fly   275 LAMAQYLMPMNFAQLLF---VYESENANREIMGMVTREVHAFQEVLN-QLCHLNIDSTEYECLRA 335
            ...|.:.:......:.:   .|..:....:.:..|........:.|: .:..||:|.||...:.|
 Worm   338 WMCANWTVQAGCEGVCYSNGAYFPKQPEAQCIPDVKGSSGRMYDSLSIPIKELNLDETEIVLMLA 402

  Fly   336 ISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARS-----ALHNY 395
            :.:|         ::::...:.||.:|.       |...::.:..|..:|:...|     |:.|.
 Worm   403 VIIF---------SDEITELADLTPAGK-------EHVRMVGNRFVRMLHHHVNSKEYGEAMENG 451

  Fly   396 IQRTHPSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISD 445
            ....:.|:.   |..:.:.::|..:|:.|             .:|.|.||
 Worm   452 DDTQNSSES---QAAVRIAKMMILLSATT-------------NLVYLTSD 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	46/85 (54%)
		NR_LBD	215..436	CDD:416257	37/239 (15%)
nhr-62	NP_492607.1	NR_DBD_HNF4A	98..173	CDD:143518	43/76 (57%)
		HOLI	299..475	CDD:214658	30/196 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910