DRSC/TRiP Functional Genomics Resources

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Protein Alignment tll and Esr1

DIOPT Version :9

Sequence 1:NP_524596.1 Gene:tll / 43656 FlyBaseID:FBgn0003720 Length:452 Species:Drosophila melanogaster
Sequence 2:NP_001289460.1 Gene:Esr1 / 13982 MGIID:1352467 Length:599 Species:Mus musculus


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tllNP_524596.1 NR_DBD_TLX 25..117 CDD:143537
NR_LBD 215..436 CDD:416257
Esr1NP_001289460.1 Modulating (transactivation AF-1), mediates interaction with MACROD1. /evidence=ECO:0000250 1..188
Interaction with DDX5, self-association. /evidence=ECO:0000250 35..178
Required for interaction with NCOA1. /evidence=ECO:0000250 35..47
Oest_recep 42..185 CDD:366947
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 147..175
NR_DBD_ER 184..265 CDD:143545
Mediates interaction with DNTTIP2. /evidence=ECO:0000250 189..314
Hinge 255..314
Interaction with AKAP13. /evidence=ECO:0000250 266..599
Self-association. /evidence=ECO:0000250 268..599
NR_LBD_ER 314..551 CDD:132747
Transactivation AF-2. /evidence=ECO:0000250 315..599
ESR1_C 556..599 CDD:372285
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 557..581
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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