Protein Alignment tll and Nr2f6

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_034280.2
• Gene: Nr2f6 / 13864
• MGIID: 1352453
• Length: 390
• Species: Mus musculus
• Alignment Length: 436
• Identity: 134/436 - (30%)
• Similarity: 190/436 - (43%)
• Gaps: 115/436 - (26%)

  Fly    22 PAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRN 86
            |....|....|.|.||.|.|||||||::.|:||..||||||||:..|.|:|.:.  |.:|:.|||
Mouse    45 PGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRD--CQIDQHHRN 107

  Fly    87 QCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGF 151
            ||:.|||:|||.|||.|:|||..|
Mouse   108 QCQYCRLKKCFRVGMRKEAVQRGR----------------------------------------- 131

  Fly   152 PGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALA 216
              :|..:||        ||..:    ||.|..|                 ..|..|..:.:.|..
Mouse   132 --IPHALPG--------PAACS----PPGATGV-----------------EPFTGPPVSELIAQL 165

  Fly   217 TRALP-PTP-------PLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFF 273
            .||.| |..       .::..:::.|.||..||..|.|.:....|.|||..||:.||..||.|.|
Mouse   166 LRAEPYPAAGRFGGGGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPAADQVALLRLSWSELF 230

  Fly   274 ILAMAQYLMPMNFAQLLF---VYESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRA 335
            :|..||..:|::.|.||.   ::.:..|....:..:. :|.||||.:::|..|.:|:.||.||:|
Mouse   231 VLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMD-QVRAFQEQVDKLGRLQVDAAEYGCLKA 294

  Fly   336 ISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTH 400
            |:||                             :.::.||.:...|.::...|:.||..|::..:
Mouse   295 IALF-----------------------------TPDACGLSDPAHVESLQEKAQVALTEYVRAQY 330

  Fly   401 PSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDM 446
            ||||.||..||..:..:..|.:..|.:|||.:.:|...|..||.||
Mouse   331 PSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDM 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	48/91 (53%)
		NR_LBD	215..436	CDD:416257	67/231 (29%)
Nr2f6	NP_034280.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		1/4 (25%)
		NR_DBD_COUP_TF	57..129	CDD:143516	44/73 (60%)
		NR_LBD_COUP-TF	157..387	CDD:132746	74/250 (30%)
		Important for dimerization. /evidence=ECO:0000250	314..390		23/63 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910