Protein Alignment tll and AgaP_AGAP009575

DIOPT Version :9

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_318587.4
• Gene: AgaP_AGAP009575 / 1278936
• VectorBaseID: AGAP009575
• Length: 761
• Species: Anopheles gambiae
• Alignment Length: 766
• Identity: 169/766 - (22%)
• Similarity: 237/766 - (30%)
• Gaps: 378/766 - (49%)

  Fly    29 LYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKS--QKQGLCVVDKTHRNQCRAC 91
            |..:|||||.|.|||||||||:||||:|||||||.|:|.|.||:  :.:|.|.||||||||||||
Mosquito     4 LLDIPCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRVYTCKAAGELKGRCPVDKTHRNQCRAC 68

  Fly    92 RLRKCFEVGMNKD---AVQH-------------------ERG----------------------P 112
            ||.|||:..||||   ..:|                   :||                      .
Mosquito    69 RLSKCFQSAMNKDGKYTARHACQEVLPSVKVLLSVRPGMKRGSFFLSPFHFAAMGRLLVIERIES 133

  Fly   113 RNSTLRRHMAM-YKDAMMGAGEMPQIPAEI------------------------------LMNTA 146
            :...::|::.| |...:..|......|:..                              |:...
Mosquito   134 KFIAIKRYVEMDYAHFIANASNTRLSPSPCKMLSPPILSLFLLRDLQKLGGFFFLVHLLSLLPLD 198

  Fly   147 ALTGFPG-----------------------------------------VPMPM------------ 158
            .|:.|||                                         :|.|:
Mosquito   199 QLSAFPGHFTHCHVLSHVSKCYNTHHPVTRRCTGLGLAKVFWEVAKHSIPKPLFTFPVPNRGSCS 263

  Fly   159 -----------------------PGLPQRAGHH--------------PAHMAAFQ-------PPP 179
                                   || |..:|..              ||..|.|:       ..|
Mosquito   264 SNRPTRAWPAETETPAPASERGPPG-PSPSGRPVREQCIVRTRNVPLPARAAPFRNGRFERAAAP 327

  Fly   180 SAAAVL-----------------------DLSVP------------------------RVPH--- 194
            |.||:|                       .|..|                        ::.|
Mosquito   328 SPAALLCTARSPYRSLVTAVKLEQNKFEFSLGTPNGSNGGNGGGAGQMPGGTNLLSPIKIEHSKM 392

  Fly   195 ------------------------------------------------HPVHQGHHGFFSPTAAY 211
                                                            |....|.....|||.
Mosquito   393 MTSVGGFEFSAAGHVQHMYKSLEPMPPSPTDSKSSISVDSPSESLTSPHSTVDGSSSVLSPTP-- 455

  Fly   212 MNA-------------------------------------------------------------- 214
            :||
Mosquito   456 INATSLSLPSPLSQNGVLDILMSTDKCQEFIQYQMHNSSIAFPGFTPVSSASITPHPPPPPPPLV 520

  Fly   215 ---LATRALPPTPP----LMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEF 272
               :|..||||..|    |...|.::||.|..||.:|.|::.:..|..|...||.|||:|||||.
Mosquito   521 PHPIALTALPPEGPTIIRLPTWEILQETTARLLFMSVRWVRCLIPFQTLSKNDQHLLLQESWKEL 585

  Fly   273 FILAMAQYLMPMNFAQLLFVYESENANREIM--GMVTREVHAFQEVLNQLCHLNIDSTEYECLRA 335
            |:|..||:.:|.:.:.||   :|......:.  .....|:...||:|.:...::.|.:|..|::|
Mosquito   586 FLLNFAQWSVPWDLSGLL---DSPQVRDRLPPDAATQLEMKTMQEILCRFRQISPDLSELGCMKA 647

  Fly   336 ISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTH 400
            :.||                             |.|:..|.:...|..:.:.|:..|..:::..:
Mosquito   648 VILF-----------------------------SPETSELCDVQPVEMLQDQAQCVLSEHVRVRY 683

  Fly   401 PSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDMYSQRK 451
            |.||.||..||.::.|:..:.|.|||.|||::|||.:.|.||:.|||...|
Mosquito   684 PRQPTRFGRLLLLLPLLRTIRSTTIETLFFKETIGTVPISRLLIDMYQMEK 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	58/133 (44%)
		NR_LBD	215..436	CDD:416257	68/226 (30%)
AgaP_AGAP009575	XP_318587.4	NR_DBD_like	1..81	CDD:295381	53/76 (70%)
		NR_LBD	530..718	CDD:299703	64/219 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BC6Q
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D34630at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820