DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and AgaP_AGAP012600

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_307453.3	Gene:	AgaP_AGAP012600 / 1268880	VectorBaseID:	AGAP012600	Length:	202	Species:	Anopheles gambiae

Alignment Length:	224	Identity:	64/224 - (28%)
Similarity:	106/224 - (47%)	Gaps:	35/224 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 EHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLLFVYE 294
            |.|.||:|..||..|.|.|::.:|..|...||::||||||.|.|:|...|:.||::.........
Mosquito     6 ETIYETSARLLFMAVKWAKNLPSFASLTFRDQVILLEESWAELFLLNAIQWCMPIDTTACTLFSL 70

  Fly   295 SENANRE------IMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLA 353
            :|:.|..      ..|.|...:....:.|.:...:.:|..|:.|::||.|||
Mosquito    71 NEHCNSANNSGFFKPGQVNDNLRILNDTLCRFKSVLVDPAEFACMKAIVLFR------------- 122

  Fly   354 NSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMH 418
                            :|:|||.:..::..:.:.|:..|..:.:...|.|..||..||.::.|:.
Mosquito   123 ----------------SEARGLKDPVQIENLQDQAQVMLAQHSRTQFPGQIARFGRLLLMLPLLR 171

  Fly   419 KVSSFTIEELFFRKTIGDITIVRLISDMY 447
            .|:|..||.::|:||||:..:.:::.|||
Mosquito   172 AVNSHKIESIYFQKTIGNTPMEKVLCDMY 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	60/211 (28%)
AgaP_AGAP012600	XP_307453.3	NR_LBD	6..189	CDD:299703	60/211 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D373206at33208
OrthoFinder	1	1.000	-	-		FOG0001683
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920