Protein Alignment tll and nr2e1

DIOPT Version :10

• Sequence 1: NP_524596.1
• Gene: tll / 43656
• FlyBaseID: FBgn0003720
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: XP_002937209.2
• Gene: nr2e1 / 100491500
• XenbaseID: XB-GENE-483554
• Length: 386
• Species: Xenopus tropicalis
• Alignment Length: 437
• Identity: 176/437 - (40%)
• Similarity: 249/437 - (56%)
• Gaps: 60/437 - (13%)

  Fly    22 PAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRN 86
            |..|:..:..:|||||.|.|||||||:||||||:|||||||||:|.|||||..||.|:|||||||
 Frog     4 PTGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRSYVCKSGNQGGCLVDKTHRN 68

  Fly    87 QCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMY----KDAMMGAGEMPQIPAEILMNTAA 147
            |||||||:||.||.|||||||||||||.||:|:.:|:|    |:.   .|..|..|:..|   .|
 Frog    69 QCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEI---NGSTPHFPSAAL---PA 127

  Fly   148 LTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYM 212
            .|.|..|....|        |...:.|....|....::.|:.| .|.:|    |....:|...|.
 Frog   128 PTFFTTVSQLEP--------HNLELTAISTTPERQTLVGLAQP-TPKYP----HEVNGAPLYLYE 179

  Fly   213 NALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAM 277
                          :|.|.:.|:||..||.::.|.|||.||:.|.:.|||:|||::|:|.|:|.:
 Frog   180 --------------VATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGI 230

  Fly   278 AQYLMPMNFAQLLFV--YESENANREIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFR 340
            ||:.:|::.:.||.|  ..|:|...:.:..:..|:.|.|||:::...|.:|:||:.||:.|..|:
 Frog   231 AQWAIPVDASTLLAVSGMNSDNTESQKLNKIISEIQALQEVVSRFRQLRLDATEFACLKCIVTFK 295

  Fly   341 KSPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPM 405
            ...|                   |:|  .:|.|....:..:||:.::|:..|::||...:|:||.
 Frog   296 AGVP-------------------PHS--GSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPC 339

  Fly   406 RFQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDMYSQRKI 452
            ||..||.::..:..::..||||:||:||||::.|.||:||||....|
 Frog   340 RFGKLLLLLPALRSINPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	70/91 (77%)
		NR_LBD	215..436	CDD:472173	72/222 (32%)
nr2e1	XP_002937209.2	NR_DBD_TLX	8..99	CDD:143537	69/90 (77%)
		NR_LBD_Tlx_PNR_like	154..370	CDD:132748	79/255 (31%)