DRSC/TRiP Functional Genomics Resources

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Protein Alignment tll and rxra

DIOPT Version :9

Sequence 1:NP_524596.1 Gene:tll / 43656 FlyBaseID:FBgn0003720 Length:452 Species:Drosophila melanogaster
Sequence 2:XP_012824678.1 Gene:rxra / 100487877 XenbaseID:XB-GENE-478718 Length:498 Species:Xenopus tropicalis


Alignment Length:464 Identity:119/464 - (25%)
Similarity:195/464 - (42%) Gaps:103/464 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 GSPDM---MDQKYNSVRLSPAASSRILYHVP--------------CKVCRDHSSGKHYGIYACDG 53
            |||.:   |:...::..:.|......:..||              |.:|.|.|||||||:|:|:|
 Frog   107 GSPQIHSPMNSVSSTEDIKPPPGINGILKVPAHPSGPMASFTKHICAICGDRSSGKHYGVYSCEG 171

  Fly    54 CAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLR 118
            |.|||||::|:...|.|:..|.  |::||..||:|:.||.:||..:||.::.::|.....:..||
 Frog   172 CKGFFKRTVRKDLTYTCRDSKD--CMIDKRQRNRCQYCRYQKCLAMGMKREGMEHHPSQHSRDLR 234

  Fly   119 --RHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSA 181
              ...|:.::...|. |..:...|                                      .|:
 Frog   235 CQAEQAVQEERQRGK-ERNENEVE--------------------------------------SSS 260

  Fly   182 AAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNW 246
            :|..|:.|.:     :....|.....|..|:.  |...|.|..|.....:|.:.|.:.||..|.|
 Frog   261 SANEDMPVEK-----ILDAEHAVEPKTETYIE--ANMGLAPNSPSDPVTNICQAADKQLFTLVEW 318

  Fly   247 IKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMN----FAQLLFVYESENANREIMGMVT 307
            .|.:..|:|||:.||::||...|.|..|.:.:...:.:.    .|..|.|:.: :|:...:|.:.
 Frog   319 AKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRN-SAHSAGVGAIF 382

  Fly   308 REVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTGSGSPNSSASAES 372
            ..|  ..|:::::..:.:|.||..|||||.||                             :.:|
 Frog   383 DRV--LTELVSKMRDMQMDKTELGCLRAIVLF-----------------------------NPDS 416

  Fly   373 RGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMHKVSSFTIEELFFRKTIGDI 437
            :||....:|.|:.....::|..|.::.:|.||.||..||..:..:..:....:|.|||.|.|||.
 Frog   417 KGLSNPSEVEALREKVYASLEAYCKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT 481

  Fly   438 TIVRLISDM 446
            .|...:.:|
 Frog   482 PIDTFLMEM 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tllNP_524596.1 NR_DBD_TLX 25..117 CDD:143537 38/105 (36%)
NR_LBD 215..436 CDD:416257 59/224 (26%)
rxraXP_012824678.1 Nuc_recep-AF1 37..143 CDD:371746 7/35 (20%)
NR_DBD_RXR 150..245 CDD:143514 39/96 (41%)
NR_LBD_RXR_like 265..476 CDD:132741 62/249 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X118
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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