DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and nr0b1

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_002933661.1	Gene:	nr0b1 / 100487043	XenbaseID:	XB-GENE-487960	Length:	278	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	52/235 - (22%)
Similarity:	99/235 - (42%)	Gaps:	51/235 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 ETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLM---------PMNFAQL 289
            :.|:..|.|.:.::|:|..|.|||:.||:||:...|....:|.:||..:         |....::
Frog    68 KAASAVLVKTLRFVKNVPCFQELPLDDQMLLVRSCWAPLLVLGLAQDKVDFETVETSEPSMLQRI 132

  Fly   290 LFVYE----SENANREIMGM---------VTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRK 341
            |...:    .::....::|.         ...|:...:|.|::..:|:|.:.||..|:.|.||..
Frog   133 LTTRQDGEKKQSQQDSLLGSPQHKLSQLPSAAEIRWIKEFLDKCWNLDISTKEYAYLKGIVLFNP 197

  Fly   342 SPPSASSTEDLANSSILTGSGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMR 406
            ..|                             ||.....:..:.::|:.||:.:::..|..:..|
Frog   198 ELP-----------------------------GLHCIQYIQGLQHEAQQALNEHVKMIHRWEQTR 233

  Fly   407 FQTLLGVVQLMHKVSSFTIEELFFRKTIGDITIVRLISDM 446
            |..|:.|:..:..|::..|.|||||..||.:.:..::.:|
Frog   234 FTKLIIVLSFLRTVNANAIAELFFRPIIGSVNMDDMLLEM 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	50/223 (22%)
nr0b1	XP_002933661.1	NR_Repeat	9..58	CDD:372889
nr0b1	XP_002933661.1	NR_LBD_Dax1	43..272	CDD:132764	51/232 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910