DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tll and asb15

DIOPT Version :9

Sequence 1:	NP_524596.1	Gene:	tll / 43656	FlyBaseID:	FBgn0003720	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_002941876.2	Gene:	asb15 / 100486500	XenbaseID:	XB-GENE-1014023	Length:	586	Species:	Xenopus tropicalis

Alignment Length:	175	Identity:	31/175 - (17%)
Similarity:	57/175 - (32%)	Gaps:	52/175 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 LRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGH--------HPAHMA 173
            ::|..||::.|..|..::..:..:...|.:...||...|:   |:....||        |.....
Frog   172 VKRWSAMHEAAKQGRRDLVSLLLKNGGNVSLEDGFGVTPL---GVAAEYGHCDILEQLIHKGGDV 233

  Fly   174 AFQPPPSAAAVLDLSVPRVP--------------------HHPVHQGHHG-------FFSPTAAY 211
            .||....::.:.|.:....|                    :.|:|:..:|       :..| |..
Frog   234 NFQAHDGSSVLSDAATGGDPDCIALLLEYGASGNIPDKEGYLPIHKAAYGGHYLALKYLIP-ATS 297

  Fly   212 MNALATRALPPTPPLMAAEH-------------IKETAAEHLFKN 243
            .||:....|.|.......::             :.|..|||:.:|
Frog   298 KNAIKRSGLSPVHSATDGQNLQCLELLIENDFDVNEVLAEHVSEN 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tll	NP_524596.1	NR_DBD_TLX	25..117	CDD:143537	31/175 (18%)
tll	NP_524596.1	NR_LBD	215..436	CDD:416257	7/42 (17%)
asb15	XP_002941876.2	PHA02875	47..>268	CDD:165206	17/98 (17%)
		ANK repeat	73..105	CDD:293786
		ANK repeat	107..138	CDD:293786
		ANK repeat	140..171	CDD:293786
		ANK repeat	175..204	CDD:293786	5/28 (18%)
		ANK repeat	206..237	CDD:293786	7/33 (21%)
		PHA02875	214..>446	CDD:165206	21/130 (16%)
		ANK repeat	239..270	CDD:293786	2/30 (7%)
		ANK repeat	343..374	CDD:293786	31/175 (18%)
		ANK repeat	378..408	CDD:293786
		ANK repeat	410..442	CDD:293786
		SOCS	529..584	CDD:413360
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000